David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Ezio Di Nucci
Jack Alan Reynolds
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Kennedy Institute of Ethics Journal 15 (2):107-134 (2005)
: The transplantation of adult human neural stem cells into prenatal non-humans offers an avenue for studying human neural cell development without direct use of human embryos. However, such experiments raise significant ethical concerns about mixing human and nonhuman materials in ways that could result in the development of human-nonhuman chimeras. This paper examines four arguments against such research, the moral taboo, species integrity, "unnaturalness," and human dignity arguments, and finds the last plausible. It argues that the transfer of human brain or retinal stem cells to nonhuman embryos would not result in the development of human-nonhuman chimeras that denigrate human dignity, provided such stem cells are dissociated. The article provides guidelines that set ethical boundaries for conducting such research that are consonant with the requirements of human dignity
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Citations of this work BETA
Monika Piotrowska (2014). Transferring Morality to Human–Nonhuman Chimeras. American Journal of Bioethics 14 (2):4-12.
Henry T. Greely, Mildred K. Cho, Linda F. Hogle & Debra M. Satz (2007). Thinking About the Human Neuron Mouse. American Journal of Bioethics 7 (5):27 – 40.
P. S. Duggan, A. W. Siegel, D. M. Blass, H. Bok, J. T. Coyle, R. Faden, J. Finkel, J. D. Gearhart, H. T. Greely, A. Hillis, A. Hoke, R. Johnson, M. Johnston, J. Kahn, D. Kerr & P. King (2009). Unintended Changes in Cognition, Mood, and Behavior Arising From Cell-Based Interventions for Neurological Conditions: Ethical Challenges. American Journal of Bioethics 9 (5):31-36.
Lawrence Burns (2007). Gunther Von Hagens' Body Worlds: Selling Beautiful Education. American Journal of Bioethics 7 (4):12 – 23.
Françoise Baylis & Jason Scott Robert (2007). Part-Human Chimeras: Worrying the Facts, Probing the Ethics. American Journal of Bioethics 7 (5):41 – 45.
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