Direct observation and unambiguous inference

Biology and Philosophy 20 (4):925-926 (2005)
In science, it sometimes occurs that an event is directly observed, and on other occasions that it is not directly observed but one can make the unambiguous inference that it has occurred. Is there any difference concerning the analysis of data arising from these two situations? In this note we show that there is such a difference in one case arising frequently in genetics. The difference derives from the fact that the ability to make the unambiguous inference arises only from a restricted form of data.
Keywords inference  observation  transmission/disequilibrium  disease locus  gene transmission
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DOI 10.1007/s10539-004-1918-z
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