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  • Robert T. Knight (2008). Consciousness Unchained: Ethical Issues and the Vegetative and Minimally Conscious State. American Journal of Bioethics 8 (9):1 – 2.
    Biomedical Ethics in Applied Ethics
    The Minimally Conscious State in Philosophy of Cognitive Science
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  • 78.5Jukka Varelius (2009). Minimally Conscious State and Human Dignity. Neuroethics 2 (1).
    Recent progress in neurosciences has improved our understanding of chronic disorders of consciousness. One example of this advancement is the emergence of the new diagnostic category of minimally conscious state (MCS). The central characteristic of MCS is impaired consciousness. Though the phenomenon now referred to as MCS pre-existed its inclusion in diagnostic classifications, the current medical ethical concepts mainly apply to patients with normal consciousness and to non-conscious patients. Accordingly, how we morally should stand with persons in minimally conscious state (...) remains unclear. In this paper, I examine whether the notion of human dignity could provide us with guidance with the moral difficulties MCS gives rise to. More precisely, I focus on the question of whether we are justified in holding that persons in minimally conscious state possess human dignity. (shrink)
    Conscious and Unconscious Memory in Philosophy of Cognitive Science
    The Minimally Conscious State in Philosophy of Cognitive Science
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  • 72.4Neil Levy & Julian Savulescu (2009). Moral Significance of Phenomenal Consciousness. Progress in Brain Research.
    Recent work in neuroimaging suggests that some patients diagnosed as being in the persistent vegetative state are actually conscious. In this paper, we critically examine this new evidence. We argue that though it remains open to alternative interpretations, it strongly suggests the presence of consciousness in some patients. However, we argue that its ethical significance is less than many people seem to think. There are several different kinds of consciousness, and though all kinds of consciousness have some ethical significance, different (...) kinds underwrite different kinds of moral value. Demonstrating that patients have phenomenal consciousness — conscious states with some kind of qualitative feel to them — shows that they are moral patients, whose welfare must be taken into consideration. But only if they are subjects of a sophisticated kind of access consciousness — where access consciousness entails global availability of information to cognitive systems — are they persons, in the technical sense of the word employed by philosophers. In this sense, being a person is having the full moral status of ordinary human beings. We call for further research which might settle whether patients who manifest signs of consciousness possess the sophisticated kind of access consciousness required for personhood. (shrink)
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  • 69.4Guy Kahane & Julian Savulescu (2009). Brain-Damaged Patients and the Moral Significance of Consciousness. The Journal of Medicine and Philosophy 34 (1):6-26.
    Neuroimaging studies of brain-damaged patients diagnosed as in the vegetative state suggest that the patients might be conscious. This might seem to raise no new ethical questions given that in related disputes both sides agree that evidence for consciousness gives strong reason to preserve life. We question this assumption. We clarify the widely held but obscure principle that consciousness is morally significant. It is hard to apply this principle to difficult cases given that philosophers of mind distinguish between a range (...) of notions of consciousness and that is unclear which of these is assumed by the principle. We suggest that the morally relevant notion is that of phenomenal consciousness and then use our analysis to interpret cases of brain damage. We argue that enjoyment of consciousness might actually give stronger moral reasons not to preserve a patient's life and, indeed, that these might be stronger when patients retain significant cognitive function. (shrink)
    Vegetative State and Coma in Philosophy of Cognitive Science
    Life Support in Applied Ethics
    Brain Imaging in Applied Ethics
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  • 69.1Richard Malone, Caroline Schnakers & Kathleen Kalmar, Does the Four Score Correctly Diagnose the Vegetative and Minimally Conscious States?
    Wijdicks and colleagues1 recently presented the Full Outline of UnResponsiveness (FOUR) scale as an alternative to the Glasgow Coma Scale (GCS)2 in the evaluation of consciousness in severely brain-damaged patients. They studied 120 patients in an intensive care setting (mainly neuro-intensive care) and claimed that “the FOUR score detects a locked-in syndrome, as well as the presence of a vegetative state.”1 We fully agree that the FOUR is advantageous in identifying locked-in patients given that it specifically tests for eye movements (...) or blinking on command. This is welcomed given that misdiagnosis of the locked-in syndrome has been shown to occur in more than half of the cases (see Laureys and colleagues3 for review). As for the diagnosis of the vegetative state, the scale explicitly tests for visual pursuit, and hence can disentangle the vegetative state from the minimally conscious state (MCS). The diagnostic criteria for MCS have been proposed4 only recently, but Wijdicks and colleagues1 do not mention the existence of this clinical entity in their article. As for the vegetative state, MCS can be encountered in the acute or subacute setting as a transitional state on the way to further recovery, or it can be a more chronic or even permanent condition. The MCS refers to patients showing inconsistent, albeit clearly discernible, minimal behavioral evidence of consciousness (eg, localization of noxious stimuli, eye fixation or tracking, reproducible movement to command, or nonfunctional verbalization).4 The FOUR scale does not test for all of the behavioral criteria required to diagnose MCS.4 It is known from the literature (see Majerus and colleagues5 for review) that about a third of patients diagnosed with vegetative state are actually in MCS, and this misdiagnosis can lead to major clinical, therapeutic, and ethical consequences. We tested the ability of the newly proposed FOUR scale to correctly diagnose the vegetative state in an acute (intensive care and neurology ward) and chronic (neurorehabilitation) setting.. (shrink)
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  • 63.9H. Gill-Thwaites & R. Munday (2004). The Sensory Modality Assessment and Rehabilitation Technique (SMaRT): A Valid and Reliable Assessment for Vegetative State and Minimally Conscious State Patients. Brain Injury 18 (12):1255-1269.
    The Minimally Conscious State in Philosophy of Cognitive Science
    Vegetative State and Coma in Philosophy of Cognitive Science
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  • 63.5Steven Laureys, Marie-Elisabeth E. Faymonville & M. Ferring (2003). Differences in Brain Metabolism Between Patients in Coma, Vegetative State, Minimally Conscious State and Locked-in Syndrome. European Journal of Neurology 10.
    The Minimally Conscious State in Philosophy of Cognitive Science
    Vegetative State and Coma in Philosophy of Cognitive Science
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  • 63.2Melanie Boly, Marie-Elisabeth E. Faymonville & Philippe Peigneux (2004). Auditory Processing in Severely Brain Injured Patients: Differences Between the Minimally Conscious State and the Persistent Vegetative State. Archives of Neurology 61 (2):233-238.
    The Minimally Conscious State in Philosophy of Cognitive Science
    Vegetative State and Coma in Philosophy of Cognitive Science
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  • 63.2Mary Terrell White (2006). Diagnosing PVS and Minimally Conscious State: The Role of Tacit Knowledge and Intuition. Journal of Clinical Ethics 17 (1):62-71.
    The Minimally Conscious State in Philosophy of Cognitive Science
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