The Metastable Genome: A Lamarckian Organ in a Darwinian World?

In Eva Jablonka & Snait Gissis (eds.), Transformations of Lamarckism: from subtle fluids to molecular biology. MIT Press (2011)
This article is arranged around two general claims and a thought experiment. I begin by suggesting that the genome should be studied as a developmental system, and that genes supervene on genomes (rather than the other way around). I move on to present a thought experiment that illustrates the implications a dynamic view of the genome has for central concepts in biology, in particular the information content of the genome, and the notion of responses to stress.
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