David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
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Studies in History and Philosophy of Science Part C 36 (2):349-371 (2005)
Philosophers have proposed various kinds of relations between Mendelian genetics and molecular biology: reduction, replacement, explanatory extension. This paper argues that the two fields are best characterized as investigating different, serially integrated, hereditary mechanisms. The mechanisms operate at different times and contain different working entities. The working entities of the mechanisms of Mendelian heredity are chromosomes, whose movements serve to segregate alleles and independently assort genes in different linkage groups. The working entities of numerous mechanisms of molecular biology are larger and smaller segments of DNA plus related molecules. Discovery of molecular DNA mechanisms filled black boxes that were noted, but unilluminated, by Mendelian genetics
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Daniel J. Nicholson (2012). The Concept of Mechanism in Biology. Studies in History and Philosophy of Science Part C 43 (1):152-163.
Brett Calcott (2009). Lineage Explanations: Explaining How Biological Mechanisms Change. British Journal for the Philosophy of Science 60 (1):51-78.
William Bechtel (2013). From Molecules to Behavior and the Clinic: Integration in Chronobiology. Studies in History and Philosophy of Science Part C 44 (4):493-502.
Ingo Brigandt (2013). Systems Biology and the Integration of Mechanistic Explanation and Mathematical Explanation. Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):477-492.
Joyce C. Havstad (2011). Problems for Natural Selection as a Mechanism. Philosophy of Science 78 (3):512-523.
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