'Saviour siblings'? The distinction between PGD with HLA tissue typing and preimplantation HLA tissue typing
David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Journal of Bioethical Inquiry 4 (1):65-70 (2007)
One of the more controversial uses of preimplantation genetic diagnosis (PGD) involves selecting embryos with a specific tissue type so that the child to be born can act as a donor to an existing sibling who requires a haematopoietic stem cell transplant. PGD with HLA tissue typing is used to select embryos that are free of a familial genetic disease and that are also a tissue match for an existing sibling who requires a transplant. Preimplantation HLA tissue typing occurs when parents select embryos that are not at risk of a familial genetic disease to be a match for an existing sibling who requires a transplant. In Victoria, Australia, applications to use PGD with HLA tissue typing are reviewed by the Infertility Treatment Authority on a case by case basis. Preimplantation HLA tissue typing is prohibited prima facie because the embryo to be tested would not be at risk for a genetic abnormality or disease. Arguments for or against the use of PGD/HLA tissue typing are based on several key issues including the commodification and welfare of the donor child. This essay aims to show that that the same arguments apply to both PGD with HLA tissue typing and Preimplantation HLA tissue typing, and that the policy distinction between the two procedures is therefore ethically inconsistent.
|Keywords||Preimplantation diagnosis Genetic screening Hematopoietic stem cell transplantation Ethics Legislation|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
No citations found.
Similar books and articles
S. Matthew Liao (2005). The Ethics of Using Genetic Engineering for Sex Selection. Journal of Medical Ethics 31 (2):116-118.
E. C. A. Asscher (2008). The Regulation of Preimplantation Genetic Diagnosis (PGD) in the Netherlands and the UK: A Comparative Study of the Regulatory Frameworks and Outcomes for PGD. Clinical Ethics 3 (4):176-179.
David Hunter, Tis but a Scratch: The Human Tissue Act and the Use of Tissue for Research, Issues for Research Ethics Committees.
Tanja Krones & Gerd Richter (2004). Preimplantation Genetic Diagnosis (PGD): European Perspectives and the German Situation. Journal of Medicine and Philosophy 29 (5):623 – 640.
R. Harries (2005). Delivering Public Policy: The Status of the Embryo and Tissue Typing. Studies in Christian Ethics 18 (1):57-74.
Jeffrey P. Kahn & Anna C. Mastroianni (2004). Creating a Stem Cell Donor: A Case Study in Reproductive Genetics. Kennedy Institute of Ethics Journal 14 (1):81-96.
N. R. Ram (2006). Britain's New Preimplantation Tissue Typing Policy: An Ethical Defence. Journal of Medical Ethics 32 (5):278-282.
K. Devolder (2005). Preimplantation HLA Typing: Having Children to Save Our Loved Ones. Journal of Medical Ethics 31 (10):582-586.
Added to index2009-01-28
Total downloads70 ( #19,045 of 1,096,498 )
Recent downloads (6 months)8 ( #22,450 of 1,096,498 )
How can I increase my downloads?