If waking and dreaming consciousness became de-differentiated, would schizophrenia result?

Consciousness and Cognition 20 (4):1059-1083 (2011)
Abstract
If both waking and dreaming consciousness are functional, their de-differentiation would be doubly detrimental. Differentiation between waking and dreaming is achieved through neuromodulation. During dreaming, without external sensory data and with mesolimbic dopaminergic input, hyper-cholinergic input almost totally suppresses the aminergic system. During waking, with sensory gates open, aminergic modulation inhibits cholinergic and mesocortical dopaminergic suppresses mesolimbic. These neuromodulatory systems are reciprocally interactive and self-organizing. As a consequence of neuromodulatory reciprocity, phenomenologically, the self and the world that appear during dreaming differ from those that emerge during waking. As a result of self-organizing, the self and the world in both states are integrated.Some loss of self-organization would precipitate a degree of de-differentiation between waking and dreaming, resulting in a hybrid state which would be expressed heterogeneously, both neurobiologically and phenomenologically. As a consequence of progressive de-differentiation, certain identifiable psychiatric disorders may emerge. Ultimately, schizophrenia, a disorganized-fragmented self, may result
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References found in this work BETA
Rita B. Ardito (2000). Dreaming as an Active Construction of Meaning. Behavioral and Brain Sciences 23 (6):907-908.
William P. Banks (1996). Korsakoff and Amnesia. Consciousness and Cognition 5 (1-2):22-26.

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Thomas Metzinger & Jennifer Michelle Windt (2007). Dreams. In D. Barrett & P. McNamara (eds.), The New Science of Dreaming. Praeger Publishers
Milton Kramer (2000). Dreaming has Content and Meaning Not Just Form. Behavioral and Brain Sciences 23 (6):959-961.
M. J. Baker (1954). Sleeping and Waking. Mind 63 (October):539-543.
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