The concept of the gene in psychiatric genetics and its consequences for the concept of mental illness
David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Poiesis and Praxis 6 (1-2):65-77 (2008)
At this point in time, it is hard to say which consequences for the concept of mental illness result from modern genetics. Current research projects are trying to find significant statistical correlations between the diagnosis of a disease and a gene locus or an endophenotype. Up until now, there has not been any identification of alleles or mutations causing mental illness. In the meantime, the relations between the genetic basis and the disease are given the term genetic vulnerability as a placeholder; this concept simplifies the complex relations between the DNA and even the simplest cell functions observed in modern genetics. According to complex gene models like the systemic theory of DNA, it will not be possible to identify the genetic factors without a precise knowledge of the factors which modulate the gene expression. The significance of genetics as part of the concept of mental illness will not be able to be defined without further progress in developmental biology and psychology. Currently, psychological theory fails to acknowledge the complexity of the relationship between the DNA and the environment. Some starting points from which to develop such an understanding can be received from developmental studies and studies of the psychophylogenesis . An interdisciplinary concept of the biological basis of the psyche is needed
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
No citations found.
Similar books and articles
Kenneth F. Schaffner (1992). Molecular Genetics, Reductionism, and Disease Concepts in Psychiatry. Journal of Medicine and Philosophy 17 (2):127-153.
C. Kenneth Waters (1994). Genes Made Molecular. Philosophy of Science 61 (2):163-185.
Peter J. Beurton, Raphael Falk & Hans-Jörg Rheinberger (eds.) (2000). The Concept of the Gene in Development and Evolution: Historical and Epistemological Perspectives. Cambridge University Press.
Brant Pridmore (2008). Review of Genes in Development: Re-Reading the Molecular Paradigm. [REVIEW] Biology and Philosophy 23 (4):579-586.
Jordan Bartol (2013). Re-Examining the Gene in Personalized Genomics. Science and Education 22 (10):2529-2546.
Thomas Fogle (1990). Are Genes Units of Inheritance? Biology and Philosophy 5 (3):349-371.
K. W. M. Fulford (1993). Mental Illness and the Mind-Brain Problem: Delusion, Belief and Searle's Theory of Intentionality. Theoretical Medicine and Bioethics 14 (2).
Petter Portin (2002). Historical Development of the Concept of the Gene. Journal of Medicine and Philosophy 27 (3):257 – 286.
Petter Portin (2009). The Elusive Concept of the Gene. Hereditas 146 (3):112-117.
Paul E. Griffiths & Karola Stotz (2006). Genes in the Postgenomic Era. Theoretical Medicine and Bioethics 27 (6):499-521.
David Michael Levin (1976). II. The Concept of Mental Illness: Working Through the Myths. Inquiry 19 (1-4):360-365.
Timothy Murphy (1982). Differential Diagnosis and Mental Illness. Journal of Medicine and Philosophy 7 (4):327-336.
Added to index2010-09-02
Total downloads12 ( #147,354 of 1,679,339 )
Recent downloads (6 months)1 ( #183,792 of 1,679,339 )
How can I increase my downloads?