The effect of vitamin a (retinoids) on pattern formation implies a uniformity of developmental mechanisms throughout the animal kingdom
David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Acta Biotheoretica 41 (4):425-445 (1993)
Retinoids are low molecular weight, lipophilic derivatives of vitamin A which have a profound effect upon the development of a diverse array of animals. Here, I review these effects on Invertebrates: a colonial hydroid, a colonial ascidian, and Vertebrates: the regenerating amphibian limb, the developing chick limb bud, the regenerating amphibian tail, the anteroposterior axis of the early embryo, the developing chick embryo skin. There is a striking uniformity of effect of retinoids on pattern formation when applied to these diverse organisms. The majority react by being posteriorized in their development, although additional effects can also be seen. Several hypotheses which can explain these results are discussed along with the deduction that they lead to: retinoids may be components of a universal developmental mechanism or they may simply act in a similar way to alter a universal developmental mechanism. In either case the experimental analysis of retinoid effects on development has important implications for the evolution of developmental mechanisms.
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
No citations found.
Similar books and articles
William C. Wimsatt (1998). Simple Systems and Phylogenetic Diversity. Philosophy of Science 65 (2):267-275.
Thomas Pradeu (2010). The Organism in Developmental Systems Theory. Biological Theory 5 (3):216-222.
Börje Ekstig (2007). A Unifying Principle of Biological and Cultural Evolution and its Implications for the Future. World Futures 63 (2):98 – 106.
Herman T. Epstein (1999). Other Brain Effects of Words. Behavioral and Brain Sciences 22 (2):287-288.
Charles T. Snowdon (1998). The Nurture of Nature: Social, Developmental, and Environmental Controls of Aggression. Behavioral and Brain Sciences 21 (3):384-385.
Larry A. Taber (2000). Pattern Formation in a Nonlinear Membrane Model for Epithelial Morphogenesis. Acta Biotheoretica 48 (1):47-63.
Tudor Baetu (2012). Defining Species: A Multi-Level Approach. Acta Biotheoretica 60 (3):239-255.
Loreta Medina (2003). Histogenetic Divisions, Developmental Mechanisms, and Cortical Evolution. Behavioral and Brain Sciences 26 (5):563-564.
Paul M. Brakefield & Vernon French (1993). Butterfly Wing Patterns. Acta Biotheoretica 41 (4):447-468.
Added to index2009-01-28
Total downloads3 ( #323,614 of 1,413,298 )
Recent downloads (6 months)1 ( #154,925 of 1,413,298 )
How can I increase my downloads?