Online research in philosophy

The Direct Argument for the incompatibility of moral responsibility and determinism is designed to side-step complaints given by compatibilist critiques of the so-called Transfer Argument. I argue that while it represents an improvement over the Transfer Argument, it loses some of its plausibility when we reflect on some metalogical issues about normal modal modeling and the semantics of natural language. More specifically, the crucial principle on which the Direct Argument depends appears doubtful where context plays a role in evaluation of normative claims.

The creation of transgenic animals has application in the following areas of pharmaceutical and biomedical research: the production of biopharmaceuticals for human use; the production of organs for xenotransplantation; and the generation of animal models for human genetic diseases. Nuclear transfer technology offers a more precise and efficient way of performing genetic modification and creating transgenic animals than the more traditional method of pronuclear microinjection. This paper will review nuclear transfer as ameans of producing transgenic animals; introduce advantages nuclear transfer technology offers in the field of animal transgenesis; and highlight some of the animal welfare issues and ethical concerns raised by the generation and use of transgenic animals in the aforementioned fields of study. Finally, the influence of objectifying language and terminology used to describe transgenic animals will be considered, and the impact of phrases such as “living bioreactor” and “spare part supplier” examined.

After some preliminaries ("I") I examine the merits of an argument which is sometimes used in an attempt to show that nuclear deterrence is morally unacceptable ("II-V"). This is the argument that deterrence is wrong because it involves a threat to do something which it is wrong to do. My conclusion is that there is something to this argument, that it is sufficient to establish a "prima facie" case against nuclear deterrence, but that it is not sufficient to establish a conclusive case against nuclear deterrence.

Harvesting human embryonic stem (hES) cells is a highly controversial field of research because it rests on the destruction of human embryos. Altering the procedure of nuclear transfer (NT) is suggested to generate hES cell lines without ethical obstacles by claiming that no embryo would be involved. While discussing the nature of an embryo and related central questions concerning their moral status and the respect they deserve, this paper argues that the entity created by somatic cell nuclear transfer (SCNT) or altered nuclear transfer (ANT) is an embryo and has the same moral status as a natural embryo. Respect for the embryo is expressed by the ethical principles of proportionality, probability and subsidiarity. This paper argues that the human embryo should only be taken for research with high ranking goals, which are proven in animal experimentation and for which there are no alternatives. This makes ANT obsolete and shows that SCNT to produce hES cells is premature at the present time.