Reducing the Dauer Larva: molecular models of biological phenomena in Caenorhabditis elegans research.
David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
One important aspect of biological explanation is detailed causal modeling of particular phenomena in limited experimental background conditions. Recognising this allows a new avenue for intertheoretic reduction to be seen. Reductions in biology are possible, when one fully recognises that a sufficient condition for a reduction in biology is a molecular model of 1) only the demonstrated causal parameters of a biological model and 2) only within a replicable experimental background. These intertheoretic identifications –which are ubiquitous in biology and form the basis of ruthless reductions (Bickle 2003)- are criticised as merely “local” (Sullivan 2009) or “fragmentary” (Schaffner 2006). However, in an instructive case, a biological model is preserved in molecular terms, and a complex biological phenomenon has been successfully reduced. In doing this the molecular model remains valid in a broader range of background conditions and meaningfully unites disparate biological phenomena.
|Keywords||Reduction eco-evo-devo nematode|
|Categories||categorize this paper)|
|External links||This entry has no external links. Add one.|
|Through your library||Only published papers are available at libraries|
References found in this work BETA
No references found.
Citations of this work BETA
No citations found.
Similar books and articles
Michal Arciszewski (2013). Reducing the Dauer Larva: Molecular Models of Biological Phenomena in Caenorhabditis Elegans Research. Synthese 190 (18):4155-4179.
Niall Shanks (2001). The Adaptive Radiation of Biological Explanation. Idealistic Studies 31 (2/3):155-168.
Kenneth F. Schaffner (1994). Interactions Among Theory, Experiment, and Technology in Molecular Biology. PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1994:192 - 205.
Janez Bregant, Andraž Stožer & Marko Cerkvenik (2010). Molecular Reduction: Reality or Fiction? [REVIEW] Synthese 172 (3):437 - 450.
Rachel A. Ankeny (2000). Fashioning Descriptive Models in Biology: Of Worms and Wiring Diagrams. Philosophy of Science 67 (3):272.
Nagarjuna G. (forthcoming). Towards a Model of Life and Cognition. In B. V. Srikantan (ed.), Foundations of Science. Center for Studies in Civilizations.
Slobodan Perovic & Paul-Antoine Miquel (2011). On Gene's Action and Reciprocal Causation. Foundations of Science 16 (1):31-46.
Joseph D. Robinson (1986). Reduction, Explanation, and the Quests of Biological Research. Philosophy of Science 53 (3):333-353.
Steven Orla Kimbrough (1979). On the Reduction of Genetics to Molecular Biology. Philosophy of Science 46 (3):389-406.
Kenneth F. Schaffner (1993). Theory Structure, Reduction, and Disciplinary Integration in Biology. Biology and Philosophy 8 (3):319-347.
Kenneth F. Schaffner (2000). Behavior at the Organismal and Molecular Levels: The Case of C. Elegans. Philosophy of Science 67 (3):288.
Ingo Brigandt (2003). Homology in Comparative, Molecular, and Evolutionary Developmental Biology: The Radiation of a Concept. Journal of Experimental Zoology (Molecular and Developmental Evolution) 299:9-17.
Philippe De Backer, Danny De Waele & Linda Van Speybroeck (2010). Ins and Outs of Systems Biology Vis-à-Vis Molecular Biology: Continuation or Clear Cut? Acta Biotheoretica 58 (1).
Philip Gasper (1992). Reduction and Instrumentalism in Genetics. Philosophy of Science 59 (4):655-670.
Added to index2012-02-09
Total downloads60 ( #21,223 of 1,088,810 )
Recent downloads (6 months)7 ( #15,213 of 1,088,810 )
How can I increase my downloads?