Evaluating the therapeutic misconception
Kennedy Institute of Ethics Journal 16 (4):353-366 (2006)
| Abstract | : The "therapeutic misconception," described by Paul Appelbaum and colleagues more than 20 years ago, refers to the tendency of participants in clinical trials to confuse the design and conduct of research with personalized medical care. Although the "therapeutic misconception" has become a term of art in research ethics, little systematic attention has been devoted to the ethical significance of this phenomenon. This article examines critically the way in which Appelbaum and colleagues formulate what is at stake in the therapeutic misconception, paying particular attention to assumptions and implications that clinical trial participation disadvantages research participants as compared with receiving standard medical care. After clarifying the ethical significance of the therapeutic misconception with respect to the decision making of patients, we offer policy recommendations for obtaining informed consent to participation in clinical trials | |||||||||
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I. S. Durand-Zaleski, C. Alberti, P. Durieux, X. Duval, S. Gottot, P. Ravaud, S. Gainotti, C. Vincent-Genod, D. Moreau & P. Amiel (2008). Informed Consent in Clinical Research in France: Assessment and Factors Associated with Therapeutic Misconception. Journal of Medical Ethics 34 (9):e16-e16.
Steven Joffe (2006). Altruistic Discourse and Therapeutic Misconception in Research Informed Consent. American Journal of Bioethics 6 (5):53-54.
Lisa R. Stines & Norah C. Feeny (2008). Unique Ethical Concerns in Clinical Trials Comparing Psychosocial and Psychopharmalogical Interventions. Ethics and Behavior 18 (2 & 3):234 – 246.
D. S. Goldberg (2011). Eschewing Definitions of the Therapeutic Misconception: A Family Resemblance Analysis. Journal of Medicine and Philosophy 36 (3):296-320.
Simon Woods, Lynn E. Hagger & Pauline McCormack (forthcoming). Therapeutic Misconception: Hope, Trust and Misconception in Paediatric Research. Health Care Analysis.
Franklin G. Miller & Alan Wertheimer (2011). The Fair Transaction Model of Informed Consent: An Alternative to Autonomous Authorization. Kennedy Institute of Ethics Journal 21 (3):201-218.
Paul S. Appelbaum (2002). Clarifying the Ethics of Clinical Research: A Path Toward Avoiding the Therapeutic Misconception. American Journal of Bioethics 2 (2):22 – 23.
Jonathan Kimmelman (2007). The Therapeutic Misconception at 25: Treatment, Research, and Confusion. Hastings Center Report 37 (6):36-42.
Maurie Markman (2004). The Research Misconception. International Journal of Applied Philosophy 18 (2):241-252.
Paul S. Appelbaum & Charles W. Lidz (2006). Re-Evaluating the Therapeutic Misconception: Response to Miller and Joffe. Kennedy Institute of Ethics Journal 16 (4):367-373.
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