Graduate studies at Western
Kennedy Institute of Ethics Journal 13 (2):93-118 (2003)
|Abstract||: When may a physician legitimately offer enrollment in a randomized clinical trial (RCT) to her patient? Two answers to this question have had a profound impact on the research ethics literature. Equipoise, as originated by Charles Fried, which we term Fried's equipoise (FE), stipulates that a physician may offer trial enrollment to her patient only when the physician is genuinely uncertain as to the preferred treatment. Clinical equipoise (CE), originated by Benjamin Freedman, requires that there exist a state of honest, professional disagreement in the community of expert practitioners as to the preferred treatment. FE and CE are widely understood as competing concepts. We argue that FE and CE offer separable and, in themselves, incomplete justifications for the conduct of clinical trials. FE articulates conditions under which the fiduciary duties of physician to patient may be upheld in the conduct of research. CE sets out a standard for the social approval of research by institutional review boards. Viewed in this way, FE and CE are not necessarily competing notions, but rather address complementary moral concerns|
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
|Through your library||Configure|
Similar books and articles
Fred Gifford (2007). So-Called "Clinical Equipoise" and the Argument From Design. Journal of Medicine and Philosophy 32 (2):135 – 150.
Paul B. Miller & Charles Weijer (2007). Revisiting Equipoise: A Response to Gifford. Kennedy Institute of Ethics Journal 17 (3):227-246.
Fred Gifford (2007). Pulling the Plug on Clinical Equipoise: A Critique of Miller and Weijer. Kennedy Institute of Ethics Journal 17 (3):203-226.
Jerry Menikoff (2003). Equipoise: Beyond Rehabilitation? Kennedy Institute of Ethics Journal 13 (4):347-351.
Fred Gifford (2000). Freedman's 'Clinical Equipoise' and Sliding-Scale All-Dimensions-Considered Equipoise'. Journal of Medicine and Philosophy 25 (4):399 – 426.
Franklin G. Miller & Howard Brody (2007). Clinical Equipoise and the Incoherence of Research Ethics. Journal of Medicine and Philosophy 32 (2):151 – 165.
Paul B. Miller & Charles Weijer (2003). Will the Real Charles Fried Please Stand Up? Kennedy Institute of Ethics Journal 13 (4):353-357.
Paul B. Miller & Charles Weijer (2006). Trust Based Obligations of the State and Physician-Researchers to Patient-Subjects. Journal of Medical Ethics 32 (9):542-547.
Winston Chiong (2006). The Real Problem with Equipoise. American Journal of Bioethics 6 (4):37 – 47.
Added to index2009-01-28
Total downloads5 ( #170,603 of 750,480 )
Recent downloads (6 months)0
How can I increase my downloads?