Graduate studies at Western
|Abstract||Smart MR contrast agents exhibit modulation of their relaxivity by specific physiological or biochemical trigger-events, while targeted MR contrast agents are envisioned to deliver the large gadolinium chelates into the target tissue. In an effort to develop novel smart and targeted MR contrast agents, the series of the DO3A based multifunctional chelating agents with the variable length of the side chain has been synthesized. They serve as valuable multipurpose precursors for contrast agents based on gadolinium chelates in the design of relaxometric MR probes. The presence of the amino group in the side chain of the macrocycle allows for conversion into various functional groups (aminophosponates, aminocarboxylates, etc.) or for conjugation with different biomolecules, dyes, and polymers. Choice of the functional groups depends on the..|
|Keywords||No keywords specified (fix it)|
No categories specified
(categorize this paper)
|Through your library||Only published papers are available at libraries|
Similar books and articles
Anurag Mishra & Josef Pfeuffer, Facile Synthesis of Gd-DO3A-EA Conjugated with DTPA: A Novel Calcium Dependent MR Contrast Agent.
A. Mayer, Unusual Calcium Sensitivity of Aminobis(Methylenephosphonate)-Containing Mri Contrast Agents.
Barteld Kooi & Allard Tamminga (2008). Moral Conflicts Between Groups of Agents. Journal of Philosophical Logic 37 (1):1-21.
M. H. Lee & N. J. Lacey (2003). The Influence of Epistemology on the Design of Artificial Agents. Minds and Machines 13 (3):367-395.
Nick Lacey & Mark Lee (2003). The Influence of Epistemology on the Design of Artificial Agents. Minds and Machines 13 (3):367-395.
İlker Yıldırım & Pınar Yolum (2009). Hybrid Models for Achieving and Maintaining Cooperative Symbiotic Groups. Mind and Society 8 (2):243-258.
Mr Sahon Bhattacharyya, Intelligent Agents in Military, Defense and Warfare: Ethical Issues and Concerns.
Rachael Briggs (2012). The Normative Standing of Group Agents. Episteme 9 (3):283-291.
Robert Demolombe (2011). Relationships Between Obligations and Actions in the Context of Institutional Agents, Human Agents or Software Agents. Artificial Intelligence and Law 19 (2-3):99-115.
Hans van Ditmarsch & Willem Labuschagne (2007). My Beliefs About Your Beliefs: A Case Study in Theory of Mind and Epistemic Logic. Synthese 155 (2):191-209.
Added to index2010-12-22
Total downloads2 ( #246,970 of 740,356 )
Recent downloads (6 months)0
How can I increase my downloads?