Understanding pathology in the context of physiological mechanisms: the practicality of a broken-normal view

Biology and Philosophy 26 (4):603-611 (2011)
The topic of disease mechanisms is of clinical importance, as our understanding of such mechanisms plays an important role in how we approach devising treatments for disease. In this paper, I critique an argument made by Mauro Nervi, in which he asserts that pathology is often better viewed in the context of distinct theoretical mechanisms. I use this critique as a starting point to argue that viewing pathology as a broken-normal, malfunctioning mechanism is more therapeutically practical and more relevant to clinical drug design, than creating a theoretical separation of pathology from physiology
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DOI 10.1007/s10539-011-9258-2
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Justin Garson (2013). The Functional Sense of Mechanism. Philosophy of Science 80 (3):317-333.
Dingmar van Eck (2015). Mechanistic Explanation in Engineering Science. European Journal for Philosophy of Science 5 (3):349-375.

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