David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Acta Biotheoretica 49 (2) (2001)
In this paper we describe a test for Nijhout's (1978, 1980a) hypothesis that the eyespot patterns on butterfly wings are the result of a threshold reaction of the epidermal cells to a concentration gradient of a diffusing degradable morphogen produced by focal cells at the centre of the future eyespot. The wings of the nymphalid butterfly, Bicyclus anynana, have a series of eyespots, each composed of a white pupil, a black disc and a gold outer ring. In earlier extirpation and transplantation experiments (Nijhout 1980a; French and Brakefield, 1995) it has been established that these eyespots are indeed organised around groups of signalling cells active during the first hours of pupal development. If these cells were to supply the positional information for eyespot formation in accordance with Nijhout's diffusion-degradation gradient model, then, when two foci are close together, the signals should sum, and this effect should be apparent in the detailed shape of the resulting pigment pattern. We give an equation for the form of the contours that would be obtained in this manner. We use this to test the morphogen gradient hypothesis on measurements of the outlines of fused eyespots obtained either by grafting focal cells close together, or by using a mutation (Spotty) that produces adjacent fused eyespots. The contours of the fused patterns were found to satisfy our equation, thus corroborating Nijhout's hypothesis to the extent possible with this particular type of experiment.
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
No citations found.
Similar books and articles
Jacqueline Lück & Hermann B. Lück (1995). Plant Cell Assemblage in Layers. Acta Biotheoretica 43 (1-2).
Robert W. Korn (1993). Apical Cells as Meristems. Acta Biotheoretica 41 (3).
E. Dulos, J. Boissonade, J. J. Perraud, B. Rudovics & P. Kepper (1996). Chemical Morphogenesis: Turing Patterns in an Experimental Chemical System. Acta Biotheoretica 44 (3-4).
Daniel M. Hausman (2009). Benevolence, Justice, Well-Being and the Health Gradient. Public Health Ethics 2 (3):235-243.
M. Aubert, M. Badoual & B. Grammaticos (2008). A Model for Short- and Long-Range Interactions of Migrating Tumour Cell. Acta Biotheoretica 56 (4).
D. Manoussaki, S. R. Lubkin, R. B. Vemon & J. D. Murray (1996). A Mechanical Model for the Formation of Vascular Networks in Vitro. Acta Biotheoretica 44 (3-4).
C. J. Weyer, P. D. Nieuwkoop & A. Lindenmayer (1977). A Diffusion Model for Mesoderm Induction in Amphibian Embryos. Acta Biotheoretica 26 (3).
Rosine Chandebois (1977). Cell Sociology and the Problem of Position Effect: Pattern Formation, Origin and Role of Gradients. Acta Biotheoretica 26 (4).
Hisao Honda, Masaharu Tanemura & Akihiro Yoshida (2000). Differentiation of Wing Epidermal Scale Cells in a Butterfly Under the Lateral Inhibition Model - Appearance of Large Cells in a Polygonal Pattern. Acta Biotheoretica 48 (2).
Paul M. Brakefield & Vernon French (1993). Butterfly Wing Patterns. Acta Biotheoretica 41 (4).
Sorry, there are not enough data points to plot this chart.
Added to index2009-01-28
Total downloads1 ( #415,073 of 1,096,585 )
Recent downloads (6 months)0
How can I increase my downloads?