A theoretical model for the association probabilities of saturated phospholipids from two-component bilayer lipid membranes
David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Acta Biotheoretica 46 (4):347-368 (1998)
The non-random mixing of biomembrane components, especially saturated phospholipids, exhibits important consequences in molecular biology. Particularly, the distribution of lipids within natural and model membranes is strongly determined by the selective association processes. These processes of phospholipids take place due to the cooperative modes in multiparticle systems as well as the specific lipid-lipid interactions both in the hydrophobic core and in the region of the polar headgroups. We demonstrated that the investigation of the selective association processes of saturated phospholipids might contribute to the insight of the lipid domains appearance inside the bilayer membranes. The association probabilities of like-pairs and cross-pairs from a binary mixture of saturated phospholipids were tested for both parallel and anti-parallel alignments of the polar headgroups. The present model confirms the experimental evidence for saturated phospholipids to have a high tendency for association in parallel configuration of the electric dipole moments of the polar headgroups whether the cross-sectional area of the polar headgroup is in an usual range of 25-55 2. There are three major lipid domains in a binary mixture of saturated phospholipids: (i) lipid domains in non-mixed phase of the first mixture component, in parallel alignment of the polar headgroups; (ii) lipid domains in non-mixed phase of the second mixture component, in anti-parallel alignment of the polar headgroups; (iii) lipid domains in mixed phase. We think that the selective association processes of phospholipids are neither exclusively, nor only involved in promoting the lipid domains appearance through bilayer phospholipid membranes.
|Keywords||Philosophy Philosophy of Biology Evolutionary Biology|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
No citations found.
Similar books and articles
Samuel Coskey & Roman Kossak (2010). The Complexity of Classification Problems for Models of Arithmetic. Bulletin of Symbolic Logic 16 (3):345-358.
Robert Batterman (1992). Quantum Chaos and Semiclassical Mechanics. PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1992:50 - 65.
Benoît Mariou (2001). Modèles Saturés Et Modèles Engendrés Par Des Indiscernables. Journal of Symbolic Logic 66 (1):325-348.
Ermek S. Nurkhaidarov & Erez Shochat (2010). Automorphisms of Saturated and Boundedly Saturated Models of Arithmetic. Notre Dame Journal of Formal Logic 52 (3):315-329.
Peter J. Taylor (1994). Shifting Frames: From Divided to Distributed Psychologies of Scientific Agents. PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1994:304 - 310.
Dale Hample, Bing Han & David Payne (2010). The Aggressiveness of Playful Arguments. Argumentation 24 (4):405-421.
Fritz Rohrlich (1990). Computer Simulation in the Physical Sciences. PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1990:507 - 518.
Rami Grossberg (1991). On Chains of Relatively Saturated Submodels of a Model Without the Order Property. Journal of Symbolic Logic 56 (1):124-128.
H. E. Baber (1987). How Bad Is Rape? Hypatia 2 (2):125 - 138.
Sorry, there are not enough data points to plot this chart.
Added to index2009-01-28
Total downloads4 ( #293,332 of 1,679,382 )
Recent downloads (6 months)1 ( #182,933 of 1,679,382 )
How can I increase my downloads?