Cliff-edged fitness functions and the persistence of schizophrenia

Behavioral and Brain Sciences 27 (6):862-863 (2004)
Abstract
Strong recent selection for social cognition may well explain the persistence of genes that predispose to schizophrenia. The specific mechanism responsible may be a skewed fitness function in which selection pushes the mean for advantageous mental traits perilously close to a “fitness cliff” where the system fails catastrophically in some individuals.
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