Knowledge-Making Distinctions in Synthetic Biology

Bioessays 30 (1):57-65 (2008)
Abstract
Synthetic biology is an increasingly high-profile area of research that can be understood as encompassing three broad approaches towards the synthesis of living systems: DNA-based device construction, genome-driven cell engineering and protocell creation. Each approach is characterized by different aims, methods and constructs, in addition to a range of positions on intellectual property and regulatory regimes. We identify subtle but important differences between the schools in relation to their treatments of genetic determinism, cellular context and complexity. These distinctions tie into two broader issues that define synthetic biology: the relationships between biology and engineering, and between synthesis and analysis. These themes also illuminate synthetic biology's connections to genetic and other forms of biological engineering, as well as to systems biology. We suggest that all these knowledge-making distinctions in synthetic biology raise fundamental questions about the nature of biological investigation and its relationship to the construction of biological components and systems.
Keywords synthetic biology  genetic determinism  scientific knowledge  biological complexity
Categories (categorize this paper)
Options
 Save to my reading list
Follow the author(s)
My bibliography
Export citation
Find it on Scholar
Edit this record
Mark as duplicate
Revision history Request removal from index Translate to english
 
Download options
PhilPapers Archive


Upload a copy of this paper     Check publisher's policy on self-archival     Papers currently archived: 11,031
External links
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library
References found in this work BETA

No references found.

Citations of this work BETA
Alexander Powell & John Dupré (2009). From Molecules to Systems: The Importance of Looking Both Ways. Studies in History and Philosophy of Biological and Biomedical Sciences 40 (1):54-64.
Tim Lewens (2013). From Bricolage to BioBricks™: Synthetic Biology and Rational Design. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):641-648.
Axel Gelfert (2013). Synthetic Biology Between Technoscience and Thing Knowledge. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (2):141-149.

View all 15 citations

Similar books and articles
David Heyd (2013). Is There Anything Unique in the Ethics of Synthetic Biology? Perspectives in Biology and Medicine 55 (4):581-589.
Analytics

Monthly downloads

Sorry, there are not enough data points to plot this chart.

Added to index

2012-10-23

Total downloads

0

Recent downloads (6 months)

0

How can I increase my downloads?

My notes
Sign in to use this feature


Discussion
Start a new thread
Order:
There  are no threads in this forum
Nothing in this forum yet.