Knowledge-Making Distinctions in Synthetic Biology
David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Bioessays 30 (1):57-65 (2008)
Synthetic biology is an increasingly high-profile area of research that can be understood as encompassing three broad approaches towards the synthesis of living systems: DNA-based device construction, genome-driven cell engineering and protocell creation. Each approach is characterized by different aims, methods and constructs, in addition to a range of positions on intellectual property and regulatory regimes. We identify subtle but important differences between the schools in relation to their treatments of genetic determinism, cellular context and complexity. These distinctions tie into two broader issues that define synthetic biology: the relationships between biology and engineering, and between synthesis and analysis. These themes also illuminate synthetic biology's connections to genetic and other forms of biological engineering, as well as to systems biology. We suggest that all these knowledge-making distinctions in synthetic biology raise fundamental questions about the nature of biological investigation and its relationship to the construction of biological components and systems.
|Keywords||synthetic biology genetic determinism scientific knowledge biological complexity|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
Alexander Powell & John Dupré (2009). From Molecules to Systems: The Importance of Looking Both Ways. Studies in History and Philosophy of Biological and Biomedical Sciences 40 (1):54-64.
Werner Callebaut (2012). Scientific Perspectivism: A Philosopher of Science's Response to the Challenge of Big Data Biology. Studies in History and Philosophy of Science Part C 43 (1):69-80.
Sune Holm (2012). Biological Interests, Normative Functions, and Synthetic Biology. Philosophy and Technology 25 (4):525-541.
Tim Lewens (2013). From Bricolage to BioBricks™: Synthetic Biology and Rational Design. Studies in History and Philosophy of Science Part C 44 (4):641-648.
Axel Gelfert (2013). Synthetic Biology Between Technoscience and Thing Knowledge. Studies in History and Philosophy of Science Part C 44 (2):141-149.
Similar books and articles
Pablo Schyfter (2012). Standing Reserves of Function: A Heideggerian Reading of Synthetic Biology. Philosophy and Technology 25 (2):199-219.
Maximilian Hörner, Nadine Reischmann & Wilfried Weber (2013). Synthetic Biology: Programming Cells for Biomedical Applications. Perspectives in Biology and Medicine 55 (4):490-502.
Pablo Schyfter (2012). Technological Biology? Things and Kinds in Synthetic Biology. Biology and Philosophy 27 (1):29-48.
Christophe Malaterre (2009). Can Synthetic Biology Shed Light on the Origin of Life? Biological Theory 4 (4):357-367.
T. Douglas & J. Savulescu (2010). Synthetic Biology and the Ethics of Knowledge. Journal of Medical Ethics 36 (11):687-693.
Amy Gutmann (2011). The Ethics of Synthetic Biology: Guiding Principles for Emerging Technologies. Hastings Center Report 41 (4):17-22.
Michel Morange (2013). Synthetic Biology: A Challenge to Mechanical Explanations in Biology? Perspectives in Biology and Medicine 55 (4):543-553.
Ute Deichmann, Michel Morange & Anthony S. Travis (2013). Editors' Introduction to Special Issue. Perspectives in Biology and Medicine 55 (4):470-472.
Maureen A. O'Malley (2009). Making Knowledge in Synthetic Biology: Design Meets Kludge. Biological Theory 4 (4):378-389.
Gregory Linshiz, Alex Goldberg, Tania Konry & Nathan J. Hillson (2013). The Fusion of Biology, Computer Science, and Engineering: Towards Efficient and Successful Synthetic Biology. Perspectives in Biology and Medicine 55 (4):503-520.
David Heyd (2013). Is There Anything Unique in the Ethics of Synthetic Biology? Perspectives in Biology and Medicine 55 (4):581-589.
Ruth Mampuys & Frans W. A. Brom (2010). The Quiet Before the Storm: Anticipating Developments in Synthetic Biology. Poiesis and Praxis 7 (3):151-168.
John I. Glass (2013). Synthetic Genomics and the Construction of a Synthetic Bacterial Cell. Perspectives in Biology and Medicine 55 (4):473-489.
Bernadette Bensaude-Vincent (2009). Synthetic Biology As a Replica of Synthetic Chemistry? Uses and Misuses of History. Biological Theory 4 (4):314-318.
Jane Calvert (2012). Systems Biology, Synthetic Biology and Data-Driven Research: A Commentary on Krohs, Callebaut, and O'Malley and Soyer. Studies in History and Philosophy of Science Part C 43 (1):81-84.
Sorry, there are not enough data points to plot this chart.
Added to index2012-10-23
Recent downloads (6 months)0
How can I increase my downloads?