Graduate studies at Western
|Abstract||Functionally distinct anatomic subdivisions of the brain can often be only a few millimeters in one or more dimensions. The study of metabolic differences in such structures by means of localized in vivo MR spectroscopy is therefore challenging, if not impossible. In fact, the spatial resolution of chemical shift imaging (CSI) in humans is typically in the range of centimeters. The aim of the present study was to optimize 1H CSI in monkeys and demonstrate the feasibility of high spatial resolutions up to 1.4 ؋ 2 ؋ 1.4 mm3. The obtained spatial resolution permitted the segregation of gray and white matter in the visual cortex based on the concentration of different metabolites and neurotrans- mitters like N-acetylaspartate, glutamate, and creatine. Con- centration ratios of white matter versus gray matter tissue as well as between metabolites matched those reported in the literature from healthy human brain, demonstrating the consis- tency and reliability of the procedure. Magn Reson Med 54: 1541–1546, 2005. © 2005 Wiley-Liss, Inc. Key words: in vivo 1H NMR spectroscopy; spectroscopic imag- ing; chemical shift imaging; spatial resolution; monkey visual cortex..|
|Keywords||No keywords specified (fix it)|
No categories specified
(categorize this paper)
|Through your library||Only published papers are available at libraries|
Similar books and articles
Claudio Babiloni, Fabrizio Vecchio, Maurizio Miriello, Gian Luca Romani & Paolo Maria Rossini (2006). Visuo-Spatial Consciousness and Parieto-Occipital Areas: A High-Resolution EEG Study. Cerebral Cortex 16 (1):37-46.
Zoe Kourtzi & Mark Augath, Integration of Local Features Into Global Shapes: Monkey and Human fMRI Studies.
Claudio Babiloni, Fabrizio Vecchio, Alessandro Bultrini, Gian Luca Romani & Paolo Maria Rossini (2006). Pre- and Poststimulus Alpha Rhythms Are Related to Conscious Visual Perception: A High-Resolution EEC Study. Cerebral Cortex 16 (12):1690-1700.
L. M. Vaina (1990). What and Where in the Human Visual System: Two Hierarchies of Visual Modules. Synthese 83 (1):49-91.
Victor A. F. Lamme, H. Landman Super, P. R. R. Roelfsema & H. Spekreijse (2000). The Role of Primary Visual Cortex (V1) in Visual Awareness. Vision Research 40 (10):1507-21.
Hannah Fitsch (2012). (A)E(s)Th(Et)Ics of Brain Imaging. Visibilities and Sayabilities in Functional Magnetic Resonance Imaging. Neuroethics 5 (3):275-283.
Simon Clavagnier, Arnaud Falchier & Henry Kennedy (2004). Long-Distance Feedback Projections to Area V1: Implications for Multisensory Integration, Spatial Awareness, and Visual Consciousness. Cognitive, Affective and Behavioral Neuroscience. Special Issue 4 (2):117-126.
Petra Stoerig, Aspasia Zontanou & Alan Cowey (2002). Aware or Unaware: Assessment of Cortical Blindness in Four Men and a Monkey. Cerebral Cortex 12 (6):565-574.
A. Cowey, P. Stoerig & C. Le Mare (1998). Effects of Unseen Stimuli on Reaction Times to Seen Stimuli in Monkeys with Blindsight. Consciousness and Cognition 7 (3):312-323.
K. G. Thompson & Jeffrey D. Schall (2000). Antecedents and Correlates of Visual Detectoin and Awareness in Macaque Prefrontal Cortex. Vision Research 40 (10):1523-38.
J. P. Gottlieb, M. Kusunoki & M. E. Goldberg (1998). The Representation of Visual Salience in Monkey Parietal Cortex. Nature 391 (6666):481-484.
Tony Ro, Bruno Breitmeyer, Philip Burton, Neel S. Singhal & David Lane (2003). Feedback Contributions to Visual Awareness in Human Occipital Cortex. Current Biology 13 (12):1038-1041.
Sorry, there are not enough data points to plot this chart.
Added to index2010-12-22
Recent downloads (6 months)0
How can I increase my downloads?