David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Behavioral and Brain Sciences 26 (1):65-82 (2003)
The concept of locally specialized functions dominates research on higher brain function and its disorders. Locally specialized functions must be complemented by processes that coordinate those functions, however, and impairment of coordinating processes may be central to some psychotic conditions. Evidence for processes that coordinate activity is provided by neurobiological and psychological studies of contextual disambiguation and dynamic grouping. Mechanisms by which this important class of cognitive functions could be achieved include those long-range connections within and between cortical regions that activate synaptic channels via NMDA-receptors, and which control gain through their voltage-dependent mode of operation. An impairment of these mechanisms is central to PCP-psychosis, and the cognitive capabilities that they could provide are impaired in some forms of schizophrenia. We conclude that impaired cognitive coordination due to reduced ion flow through NMDA-channels is involved in schizophrenia, and we suggest that it may also be involved in other disorders. This perspective suggests several ways in which further research could enhance our understanding of cognitive coordination, its neural basis, and its relevance to psychopathology. Key Words: attention; cerebral cortex; cognitive coordination; cognitive neuropsychiatry; cognitive neuropsychology; context disorganization; Gamma rhythms; Gestalt theory; glutamate; grouping; memory; NMDA-receptors; PCP-psychosis; perceptual organization; schizophrenia.
|Keywords||attention cerebral cortex cognitive coordination cognitive neuropsychiatry cognitive neuropsychology context disorganization Gamma rhythms Gestalt theory glutamate grouping memory NMDA-receptors PCP-psychosis perceptual organization schizophrenia|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
Elisabeth Pacherie & Jean-Remy Martin (2013). Out of Nowhere: Thought Insertion, Ownership and Context-Integration. Consciousness and Cognition 22 (1):111-122.
Jean-Rémy Martin & Elisabeth Pacherie (2013). Out of Nowhere: Thought Insertion, Ownership and Context-Integration. Consciousness and Cognition 22 (1):111-122.
Jean-Rémy Martin (2013). Experiences of Activity and Causality in Schizophrenia: When Predictive Deficits Lead to a Retrospective Over-Binding. Consciousness and Cognition 22 (4):1361-1374.
Louis Sass, Elizabeth Pienkos & Barnaby Nelson (2013). IntrospectionIntrospection and Schizophrenia: A Comparative Investigation of Anomalous Self Experiences. Consciousness and Cognition 22 (3):853-867.
Louis Sass (2007). Contradictions of Emotion in Schizophrenia. Cognition and Emotion 21 (2):351-390.
Similar books and articles
Armando Bertone, Laurent Mottron & Jocelyn Faubert (2004). Autism and Schizophrenia: Similar Perceptual Consequence, Different Neurobiological Etiology? Behavioral and Brain Sciences 27 (4):592-593.
Steven L. Bressler (2003). Context Rules. Behavioral and Brain Sciences 26 (1):85-85.
Jocelyn Faubert & Armando Bertone (2004). A Common Link Between Aging, Schizophrenia, and Autism? Behavioral and Brain Sciences 27 (4):593-594.
William A. Phillips & Steven M. Silverstein (2004). Unity and Diversity in Disorders of Cognitive Coordination. Behavioral and Brain Sciences 27 (4):594-599.
Ruth Condray & Stuart R. Steinhauer (2003). Mechanisms of Disrupted Language Comprehension in Schizophrenia. Behavioral and Brain Sciences 26 (1):87-88.
Diane C. Gooding & Jacqueline G. Braun (2003). Cognitive Coordination Deficits: A Necessary but Not Sufficient Factor in the Development of Schizophrenia. Behavioral and Brain Sciences 26 (1):89-90.
Leanne M. Williams, Kwang-Hyuk Lee, Albert Haig & Evian Gordon (2003). High-Frequency Synchronisation in Schizophrenia: Too Much or Too Little? Behavioral and Brain Sciences 26 (1):109-110.
J. P. Ginsberg (2003). Setting Domain Boundaries for Convergence of Biological and Psychological Perspectives on Cognitive Coordination in Schizophrenia. Behavioral and Brain Sciences 26 (1):88-89.
Michael A. Kisley & Deana B. Davalos (2003). Is Sensory Gating a Form of Cognitive Coordination? Behavioral and Brain Sciences 26 (1):94-95.
Daniel C. Javitt (2003). Peeling the Onion: NMDA Dysfunction as a Unifying Model in Schizophrenia. Behavioral and Brain Sciences 26 (1):93-94.
Added to index2009-01-28
Total downloads18 ( #152,160 of 1,725,935 )
Recent downloads (6 months)2 ( #268,758 of 1,725,935 )
How can I increase my downloads?