David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
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Studies in History and Philosophy of Biological and Biomedical Sciences 40 (1):54-64 (2009)
Although molecular biology has meant different things at different times, the term is often associated with a tendency to view cellular causation as conforming to simple linear schemas in which macro-scale effects are specified by micro-scale structures. The early achievements of molecular biologists were important for the formation of such an outlook, one to which the discovery of recombinant DNA techniques, and a number of other findings, gave new life even after the complexity of genotype–phenotype
relations had become apparent. Against this background we outline how a range of scientific developments and conceptual considerations can be regarded as enabling and perhaps necessitating contemporary systems approaches. We suggest that philosophical ideas have a valuable part to play in making sense of complex scientific and disciplinary issues.
|Keywords||molecular biology systems biology reductionism emergence mechanism networks|
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References found in this work BETA
Mark A. Bedau (1997). Weak Emergence. Philosophical Perspectives 11 (s11):375-399.
Carl F. Craver & William Bechtel (2007). Top-Down Causation Without Top-Down Causes. Biology and Philosophy 22 (4):547-563.
Soraya De Chadarevian (1996). Sequences, Conformation, Information: Biochemists and Molecular Biologists in the 1950s. [REVIEW] Journal of the History of Biology 29 (3):361-386.
Soraya de Chadarevian (1998). Of Worms and Programmes: Caenorhabditis Elegans and the Study of Development. Studies in History and Philosophy of Science Part C 29 (1):81-105.
John Dupre (2002). The Lure of the Simplistic. Philosophy of Science 69 (S3):S284-S293.
Citations of this work BETA
Steven French (2010). The Interdependence of Structure, Objects and Dependence. Synthese 175 (S1):89 - 109.
Andrew Reynolds (2010). The Redoubtable Cell. Studies in History and Philosophy of Science Part C 41 (3):194-201.
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