David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Studies in History and Philosophy of Biological and Biomedical Sciences 40 (1):54-64 (2009)
Although molecular biology has meant different things at different times, the term is often associated with a tendency to view cellular causation as conforming to simple linear schemas in which macro-scale effects are specified by micro-scale structures. The early achievements of molecular biologists were important for the formation of such an outlook, one to which the discovery of recombinant DNA techniques, and a number of other findings, gave new life even after the complexity of genotype–phenotype
relations had become apparent. Against this background we outline how a range of scientific developments and conceptual considerations can be regarded as enabling and perhaps necessitating contemporary systems approaches. We suggest that philosophical ideas have a valuable part to play in making sense of complex scientific and disciplinary issues.
|Keywords||molecular biology systems biology reductionism emergence mechanism networks|
|Categories||categorize this paper)|
|Through your library||Configure|
Similar books and articles
James Elser & Andrew Hamilton (2007). Stoichiometry and the New Biology: The Future Is Now. PLoS Biology 5:181-183.
Alexander Rosenberg (2006). Darwinian Reductionism, or, How to Stop Worrying and Love Molecular Biology. University of Chicago Press.
Richard M. Burian (2007). On MicroRNA and the Need for Exploratory Experimentation in Post-Genomic Molecular Biology. History and Philosophy of the Life Sciences 29 (3):285 - 311.
Alexander Powell (2009). Molecules, Cells and Minds: Aspects of Bioscientific Explanation. Dissertation, University of Exeter
Alexander Powell, Maureen A. O'Malley, Staffan Mueller-Wille, Jane Calvert & John Dupré (2007). Disciplinary Baptisms: A Comparison of the Naming Stories of Genetics, Molecular Biology, Genomics and Systems Biology. History and Philosophy of the Life Sciences 29 (1):5-32.
Tudor M. Baetu (2011). Mechanism Schemas and the Relationship Between Biological Theories. In Phyllis McKay Illari Federica Russo (ed.), Causality in the Sciences. Oxford University Press.
Darrell P. Rowbottom (2011). Approximations, Idealizations and 'Experiments' at the Physics-Biology Interface. Studies in History and Philosophy of Biological and Biomedical Sciences 42 (2):145-154.
Fred C. Boogerd, Frank J. Bruggeman, Jan-Hendrik S. Hofmeyr & Hans V. Westerhoff (eds.) (2007). Systems Biology: Philosophical Foundations. Elsevier.
Hans-Jörg Rheinberger (1993). Experiment Und Orientierung: Frühe Systeme der in Vitro Proteinbiosynthese. NTM International Journal of History and Ethics of Natural Sciences, Technology and Medicine 1 (1):237-253.
Added to index2010-05-06
Total downloads39 ( #36,208 of 1,006,301 )
Recent downloads (6 months)1 ( #64,735 of 1,006,301 )
How can I increase my downloads?