David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Journal of Medical Ethics 38 (9):552-558 (2012)
Bioethicists have long debated the content of sponsors and researchers' obligations of justice in international clinical research. However, there has been little empirical investigation as to whether and how obligations of responsiveness, ancillary care, post-trial benefits and research capacity strengthening are upheld in low- and middle-income country settings. In this paper, the authors argue that research ethics guidelines need to be more informed by international research practice. Practical guidance on how to fulfil these obligations is needed if research groups and other actors are to successfully translate them into practice because doing so is often a complicated, context-specific process. Case study research methods offer one avenue for collecting data to develop this guidance. The authors describe how such methods have been used in relation to the Shoklo Malaria Research Unit's vivax malaria treatment (VHX) trial (NCT01074905). Relying on the VHX trial example, the paper shows how information can be gathered from not only international clinical researchers but also trial participants, community advisory board members and research funder representatives in order to: (1) measure evidence of responsiveness, provision of ancillary care, access to post-trial benefits and research capacity strengthening in international clinical research; and (2) identify the contextual factors and roles and responsibilities that were instrumental in the fulfilment of these ethical obligations. Such empirical work is necessary to inform the articulation of obligations of justice in international research and to develop guidance on how to fulfil them in order to facilitate better adherence to guidelines' requirements
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
No citations found.
Similar books and articles
Bridget Pratt & Bebe Loff (2011). Justice in International Clinical Research. Developing World Bioethics 11 (2):75-81.
Bridget Pratt & Bebe Loff (2013). A Framework to Link International Clinical Research to the Promotion of Justice in Global Health. Bioethics 27 (3):387-396.
Bridget Pratt & Bebe Loff (2013). Linking International Research to Global Health Equity: The Limited Contribution of Bioethics. Bioethics 27 (4):208-214.
Bridget Pratt, Deborah Zion & Bebe Loff (2012). Evaluating the Capacity of Theories of Justice to Serve as a Justice Framework for International Clinical Research. American Journal of Bioethics 12 (11):30-41.
Robert O. Keohane (1989). Closing the Fairness-Practice Gap. Ethics and International Affairs 3 (1):101–116.
Alex John London (2005). Justice and the Human Development Approach to International Research. Hastings Center Report 35 (1):24-37.
Gillian Brock (2008). Taxation and Global Justice: Closing the Gap Between Theory and Practice. Journal of Social Philosophy 39 (2):161–184.
David Luban (2006). Jon Elster, Closing the Books: Transitional Justice in Historical Perspective:Closing the Books: Transitional Justice in Historical Perspective. Ethics 116 (2):409-412.
Jason Helms (2013). Discourse, Figure by Jean-François Lyotard (Review). Philosophy and Rhetoric 46 (1):122-130.
Douglas Odegard (1964). On Closing the Truth-Value Gap. Analysis 25 (1):10 - 12.
Sean Dorrance Kelly (2005). Closing the Gap. The Harvard Review of Philosophy 13 (2):4-24.
Marcus Arvan (2012). Reconceptualizing Human Rights. Journal of Global Ethics 8 (1):91-105.
Andrzej Górski (2006). The Responsible Conduct of Basic and Clinical Research. Science and Engineering Ethics 12 (1):3-4.
Added to index2012-03-17
Total downloads5 ( #234,882 of 1,099,963 )
Recent downloads (6 months)2 ( #190,060 of 1,099,963 )
How can I increase my downloads?