The Philosophical Origins of Mitchell's Chemiosmotic Concepts: The Personal Factor in Scientific Theory Formulation
Graduate studies at Western
Journal of the History of Biology 34 (3):433 - 460 (2001)
|Abstract||Mitchell's formulation of the chemiosmotic theory of oxidative phosphorylation in 1961 lacked any experimental support for its three central postulates. The path by which Mitchell reached this theory is explored. A major factor was the role of Mitchell's philosophical system conceived in his student days at Cambridge. This system appears to have become a tacit influence on his work in the sense that Polanyi understood all knowledge to be generated by an interaction between tacit and explicit knowing. Early in his life Mitchell had evolved a simple philosophy based on fluctoids, fluctids and statids which was developed in a thesis submitted for the Ph.D. at the University of Cambridge, England. This aspect of his work was rejected by the examiners and became a tacit element in his intellectual development. It is argued from his various publications that this philosophy can be traced as an underlying theme behind much of Mitchell's theoretical writing in the 50's leading, through his notion of vectorial metabolism, to the formulation and amplification of the chemiosmotic theory in the sixties. This philosophy formed the basis for Mitchell of his understanding of biological systems and gave him his unique approach to cell biology.|
|Keywords||bioenergetics chemiosmotic theory fluctoids membrane transport,/kwd> Peter Mitchell Michael Polanyi oxidative phosphorylation vectorial metabolism|
|Categories||categorize this paper)|
|Through your library||Configure|
Similar books and articles
Bruce H. Weber & John N. Prebble (2006). An Issue of Originality and Priority: The Correspondence and Theories of Oxidative Phosphorylation of Peter Mitchell and Robert J.P. Williams, 1961-1980. [REVIEW] Journal of the History of Biology 39 (1):125 - 163.
David Crawford (2011). Review of Sandra D. Mitchell: Unsimple Truths: Science, Complexity, and Policy. [REVIEW] Biology and Philosophy 26 (2):305-313.
Lawrence E. Mitchell (1998). Stacked Deck: A Story of Selfishness in America. Temple University Press.
D. Rita Alfonso (2009). Permeability and Impermeability in John Cameron Mitchell's Shortbus. Radical Philosophy Review 12 (1/2):121-136.
Paul Lewis, Walter Gulick & Mark T. Mitchell (2007). A Brief Symposium on Mark Mitchell's Michael Polanyi. Tradition and Discovery 34 (2):30-38.
Sandra D. Mitchell (2009). Unsimple Truths: Science, Complexity, and Policy. The University of Chicago Press Chicago and London.
Basil Mitchell, William J. Abraham & Steven W. Holtzer (eds.) (1987). The Rationality of Religious Belief: Essays in Honour of Basil Mitchell. Oxford University Press.
W. M. Davies (1999). Sir William Mitchell and the "New Mysterianism". Australasian Journal of Philosophy 77 (3):253-73.
Mitchell S. Green (1995). Origins of Analytical Philosophy. Philosophical Review 104 (4):613-615.
Mitchell G. Ash & Thomas Sturm (eds.) (2007). Psychology’s Territories: Historical and Contemporary Perspectives From Different Disciplines. Erlbaum.
Peter J. Mehl (1991). In the Twilight of Modernity: MacIntyre and Mitchell on Moral Traditions and Their Assessment. Journal of Religious Ethics 19 (1):21 - 54.
Basil Mitchell (ed.) (1957). Faith and Logic. London, Allen & Unwin.
Mitchell S. Green (2007). Self-Expression. Oxford University Press.
Anne Drapkin Lyerly, Lisa M. Mitchell, Elizabeth Mitchell Armstrong, Lisa H. Harris, Rebecca Kukla, Miriam Kuppermann & Margaret Olivia Little (2009). Risk and the Pregnant Body. Hastings Center Report 39 (6):34-42.
James McBain (2004). Moral Callings and the Decision to Have Children – A Response to Mitchell. Contemporary Philosophy 2004 (25):3&4.
Added to index2011-05-29
Total downloads5 ( #170,343 of 738,608 )
Recent downloads (6 months)1 ( #61,778 of 738,608 )
How can I increase my downloads?