Abstract
Physics takes for granted that interacting physical systems with no common history are independent, before their interaction. This principle is time-asymmetric, for no such restriction applies to systems with no common future, after an interaction. The time-asymmetry is normally attributed to boundary conditions. I argue that there are two distinct independence principles of this kind at work in contemporary physics, one of which cannot be attributed to boundary conditions, and therefore conflicts with the assumed T (or CPT) symmetry of microphysics. I note that this may have interesting ramifications in quantum mechanics.