David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Theoretical Medicine and Bioethics 24 (1):31-58 (2003)
To discern the ethical issues involved incurrent gene therapy research, to explore theproblems inherent in possible future genetherapies, and to encourage debate within thescientific community about ethical questionsrelevant to both, we surveyed American Societyof Human Genetics scientists who engage inhuman genetics research. This study of theopinions of U.S. scientific experts about theethical issues discussed in the literature ongene therapy contributes systematic data on theattitudes of those working in the field as wellas elaborative comments. Our survey finds thatrespondents are highly supportive of thepotential use of somatic cell gene therapy tocure serious diseases in adults and children aswell as prospective offspring. A clearmajority, however, believe that using suchgenetic techniques for enhancement purposes isunacceptable. Delineating the line betweendisease/disorder and improvement/enhancementposes a problem not easily resolved and oneconducive to the growth of slippery-slopeapprehensions. The majority of respondents alsoadvocate germ-line therapy, in theory at least,and under similar restrictions, but theyrecognize the roadblock that the existence ofunanticipated negative consequences currentlypresents. Another complex matter involvestrying to determine appropriate reasons forchoosing target diseases for research, forwhich the dichotomy between rare single-geneand common multifactorial diseases reveals anongoing dilemma.
|Keywords||bioethics biomedical ethics disease enhancement gene therapy genetic engineering genetics germ-line therapy health human genetics opinion survey|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
No citations found.
Similar books and articles
Kathleen Nolan (1991). Commentary: How Do We Think About the Ethics of Human Germ-Line Genetic Therapy? Journal of Medicine and Philosophy 16 (6):613-619.
Gregory Fowler, Eric T. Juengst & Burke K. Zimmerman (1989). Germ-Line Gene Therapy and the Clinical Ethos of Medical Genetics. Theoretical Medicine and Bioethics 10 (2).
Maurizio Salvi (2001). Shaping Individuality: Human Inheritable Germ Line Gene Modification. Theoretical Medicine and Bioethics 22 (6):527-542.
Torbjörn Tännsjö (1993). Should We Change the Human Genome? Theoretical Medicine and Bioethics 14 (3).
John C. Fletcher (1985). Ethical Issues in and Beyond Prospective Clinical Trials of Human Gene Therapy. Journal of Medicine and Philosophy 10 (3):293-310.
W. French Anderson (1989). Human Gene Therapy: Why Draw a Line? Journal of Medicine and Philosophy 14 (6):681-693.
W. French Anderson (1985). Human Gene Therapy: Scientific and Ethical Considerations. Journal of Medicine and Philosophy 10 (3):275-292.
Bernard M. Gert (1991). Genetic Disorders and the Ethical Status of Germ-Line Gene Therapy. Journal of Medicine and Philosophy 16 (6):667-683.
Gerd Richter & Matthew D. Bacchetta (1998). Interventions in the Human Genome: Some Moral and Ethical Considerations. Journal of Medicine and Philosophy 23 (3):303 – 317.
Added to index2009-01-28
Total downloads15 ( #161,941 of 1,700,244 )
Recent downloads (6 months)5 ( #128,702 of 1,700,244 )
How can I increase my downloads?