Acta Biotheoretica 43 (1-2) (1995)
|Abstract||This paper deals with the application of the metabolic control theory, especially the measurement of control coefficients, to the threonine pathway inE. coli. The control coefficient of a step on a metabolic flux quantitatively assesses the flux response to the step variations. This concept is particularly relevant both in pathological situations (decrease in the activity of an enzymatic step in the metabolism) and in biotechnologies, where, on the contrary steps are amplified.Measurement of the control coefficients of the steps of a metabolic network makes it possible to know those whose amplification should lead to a simultaneous increase in the fluxes.|
|Keywords||No keywords specified (fix it)|
|Through your library||Configure|
Similar books and articles
A. M. Perault-Staub, P. Tracqui & J. F. Staub (1992). Modelling of in Vivo Calcium Metabolism. I. Optimal Cooperation Between Constant and Rhythmic Behaviours. Acta Biotheoretica 40 (2-3).
C. M. Asmus (2009). Restricted Arrow. Journal of Philosophical Logic 38 (4):405 - 431.
Duijn, Marc van, Keijzer, F. A. & Franken, Daan, Principles of Minimal Cognition. Casting Cognition as Sensorimotor Coordination.
F. Fassy, J.-F. Hervagaule, T. Letellier, J. P. Mazat, C. Reder & P. Villalobos (1992). Application of the Metabolic Control Theory to the Study of the Dynamics of Substrate Cycles. Acta Biotheoretica 40 (2-3).
James Canvin, Susan Grant, Primrose Freestone, Istvan Toth, Mirella Trinei, Kishor Modha, Dominique Cellier & Vic Norris (1998). Rapid Growth Mutants of Escherichia Coli. Acta Biotheoretica 46 (2).
Jean-Pierre Mazat & Thierry Letellier (1991). La Theorie du Controle du Metabolisme Controle Et Regulation. Acta Biotheoretica 39 (3-4).
Bernard Korzeniewski & Jean-Pierre Mazat (1996). Theoretical Studies on Control of Oxidative Phosphorylation in Muscle Mitochondria at Different Energy Demands and Oxygen Concentrations. Acta Biotheoretica 44 (3-4).
Hans V. Westerhoff & Daniel Kahn (1993). Control Involving Metabolism and Gene Expression. Acta Biotheoretica 41 (1-2).
Dominique de Vienne, Bruno Bost, Julie Fiévet & Christine Dillmann (2001). Optimisation of Enzyme Concentrations for Unbranched Reaction Chains: The Concept of Combined Response Coefficient. Acta Biotheoretica 49 (4).
Sorry, there are not enough data points to plot this chart.
Added to index2009-01-28
Recent downloads (6 months)0
How can I increase my downloads?