Abstract
The paper approaches the topic of what a general philosophy of science could mean today from the perspective of a historical epistemology. Consequently, in a first step, the paper looks at the notion of generality in the sciences, and how it evolved over time, on the example of the life sciences. In the second part of the paper, the urgency of a general philosophy of science is located in the history of philosophy of science. Two attempts at the beginning of the twentieth century are particularly highlighted: that of Karl Popper and that of Martin Heidegger. Both of them concentrate, albeit in widely different form, on the phenomenon of research as an open-ended process. This trend is even more pronounced in Gaston Bachelard’s version of a historical epistemology, whose work is taken as a point of reference for a general historical epistemology of research. The paper concludes with a plea to look, with Georges Canguilhem, at the history of the sciences as a laboratory for epistemology.