David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Kennedy Institute of Ethics Journal 21 (2):141-179 (2011)
One of the key ethical requirements for biomedical research is that it have an acceptable risk-benefit profile (Emanuel, Wendler, and Grady 2000). The International Conference of Harmonization guidelines mandate that clinical trials should be initiated and continued only if “the anticipated benefits justify the risks” (1996). Guidelines from the Council for International Organizations of Medical Sciences state that biomedical research is acceptable only if the “potential benefits and risks are reasonably balanced” (2002). U.S. federal regulations require that the “risks to subjects” be “reasonable in relation to anticipated benefits, if any, to subjects and the importance of the knowledge” to be gained from the ..
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
Rosemarie D. L. C. Bernabe, Ghislaine J. M. W. Van Thiel, Jan A. M. Raaijmakers & Johannes J. M. Van Delden (2013). News Media Coverage of Euthanasia: A Content Analysis of Dutch National Newspapers. [REVIEW] Bmc Medical Ethics 2012 13 14 (1):6-.
Johannes J. M. Van Delden Rosemarie D. L. C. Bernabe, Ghislaine J. M. W. Van Thiel, Jan A. M. Raaijmakers (2012). The Risk-Benefit Task of Research Ethics Committees: An Evaluation of Current Approaches and the Need to Incorporate Decision Studies Methods. [REVIEW] BMC Medical Ethics 13 (1):6.
Similar books and articles
Annette Rid David Wendler (2011). A Framework for Risk-Benefit Evaluations in Biomedical Research. Kennedy Institute of Ethics Journal 21 (2):141-179.
Charles Weijer, The Ethical Analysis of Risks and Potential Benefits in Human Subjects Research: History, Theory, and Implications for U.S. Regulation.
Janet Malek (2007). Understanding Risks and Benefits in Research on Reproductive Genetic Technologies. Journal of Medicine and Philosophy 32 (4):339 – 358.
David Wendler & Emily Abdoler (2011). Does It Matter Whether Investigators Intend to Benefit Research Subjects? Kennedy Institute of Ethics Journal 20 (4):353-370.
David Wendler (2012). A New Justification for Pediatric Research Without the Potential for Clinical Benefit. American Journal of Bioethics 12 (1):23 - 31.
Sara Svensson & Sven Ove Hansson (2007). Protecting People in Research: A Comparison Between Biomedical and Traffic Research. [REVIEW] Science and Engineering Ethics 13 (1):99-115.
Andrzej Górski (2006). The Responsible Conduct of Basic and Clinical Research. Science and Engineering Ethics 12 (1):3-4.
Charles Weijer & Paul B. Miller, When Are Research Risks Reasonable in Relation to Anticipated Benefits?
Charles Weijer & Paul B. Miller (2007). Refuting the Net Risks Test: A Response to Wendler and Miller's "Assessing Research Risks Systematically". Journal of Medical Ethics 33 (8):487-490.
Eric Chwang (2010). Against Risk-Benefit Review of Prisoner Research. Bioethics 24 (1):14-22.
Robert C. Hughes (2014). Justifying Community Benefit Requirements in International Research. Bioethics 28 (8):397-404.
Angela Ballantyne (2008). Benefits to Research Subjects in International Trials: Do They Reduce Exploitation or Increase Undue Inducement? Developing World Bioethics 8 (3):178-191.
Paul Litton, Non-Beneficial Pediatric Research and the Best Interests Standard: A Legal and Ethical Reconciliation.
Alex Rajczi (2004). Making Risk-Benefit Assessments of Medical Research Protocols. Journal of Law, Medicine and Ethics 32 (2):338-348.
Georg Spielthenner (2012). Risk-Benefit Analysis: From a Logical Point of View. [REVIEW] Journal of Bioethical Inquiry 9 (2):161-170.
Added to index2011-06-06
Total downloads24 ( #85,444 of 1,692,519 )
Recent downloads (6 months)6 ( #38,243 of 1,692,519 )
How can I increase my downloads?