Systems bioethics and stem cell biology
Journal of Bioethical Inquiry 3 (1-2) (2006)
| Abstract | The complexities of modern science are not adequately reflected in many bioethical discussions. This is especially problematic in highly contested cases where there is significant pressure to generate clinical applications fast, as in stem cell research. In those cases a more integrated approach to bioethics, which we call systems bioethics, can provide a useful framework to address ethical and policy issues. Much as systems biology brings together different experimental and methodological approaches in an integrative way, systems bioethics integrates aspects of the history and philosophy of science, social and political theory, and normative analysis with the science in question. In this paper we outline how a careful analysis of the science of stem cell research can help to refocus the discussions related to the clinical applications of stem cells. We show how inaccurate or inadequate scientific assumptions help to create a set of unrealistic expectations and badly inform ethical deliberations and policy development. Systems bioethics offers resources for moving beyond the current impasse. | |||||||||
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Insoo Hyun (2010). Allowing Innovative Stem Cell-Based Therapies Outside of Clinical Trials: Ethical and Policy Challenges. Journal of Law, Medicine and Ethics 38 (2):277-285.
David Magnus (2010). Translating Stem Cell Research: Challenges at the Research Frontier. Journal of Law, Medicine and Ethics 38 (2):267-276.
Mark T. Brown (2009). Moral Complicity in Induced Pluripotent Stem Cell Research. Kennedy Institute of Ethics Journal 19 (1):pp. 1-22.
Jane Maienschein (2002). Stem Cell Research: A Target Article Collection Part II - What's in a Name: Embryos, Clones, and Stem Cells. American Journal of Bioethics 2 (1):12 – 19.
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Nikolaus Knoepffler (2004). Stem Cell Research: An Ethical Evaluation of Policy Options. Kennedy Institute of Ethics Journal 14 (1):55-74.
Melinda Fagan (2012). Waddington Redux: Models and Explanation in Stem Cell and Systems Biology. Biology and Philosophy 27 (2):179-213.
Melinda B. Fagan (2011). Social Experiments in Stem Cell Biology. Perspectives on Science 19 (3):235-262.
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