RED: ADHD under the “micro-scope” of the rat model

Behavioral and Brain Sciences 28 (3):439-440 (2005)
Derived from a rat model, the theory of Sagvolden et al. offers an all-explanatory model of attention-deficit/hyperactivity disorder (ADHD) anatomy, behaviour, and cognition as being caused predominantly by a hypo-dopaminergic mesolimbic (affecting the mesocortical and nigrostriatal) system, leading to abnormal reward and extinction processes. This model suffers from oversimplification and reductionism, reflecting the limitations of the use of animal models to explain higher mental disorders.
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DOI 10.1017/S0140525X05350072
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Susan Hawthorne (2010). Embedding Values: How Science and Society Jointly Valence a Concept—the Case of ADHD. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 41 (1):21-31.

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