David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Philosophy, Ethics, and Humanities in Medicine 3 (1):23 (2008)
The ideology of evidence-base medicine (EBM) has dramatically altered the way we think, conceptualize, philosophize and practice medicine. One of its major pillars is the appraisal and classification of evidence. Although important and beneficial, this process currently lacks detail and is in need of reform. In particular, it largely focuses on three key dimensions (design, [type I] alpha error and beta [type II] error) to grade the quality of evidence and often omits other crucial aspects of evidence such as biological plausibility, reproducibility, generalizability, temporality, consistency and coherence. It also over-values the randomized trial and meta-analytical techniques, discounts the biasing effect of single centre execution and gives insufficient weight to large and detailed observational studies. Unless these aspects are progressively included into systems for grading, evaluating and classifying evidence and duly empirically assessed (according to the EBM paradigm), the EBM process and movement will remain open to criticism of being more evidence-biased than evidence-based
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
Sarah J. L. Edwards (2011). Assessing the Remedy: The Case for Contracts in Clinical Trials. American Journal of Bioethics 11 (4):3-12.
Roger Kerry, Thor Eirik Eriksen, Svein Anders Noer Lie, Stephen Mumford & Rani Lill Anjum (2012). Causation and Evidence-Based Practive - an Ontological Review. Journal of Evaluation in Clinical Practice 18 (5):1006-1012.
Similar books and articles
Marcin Waligora (2013). A European Consistency for Functioning of RECs? We Just Lost Our Chance. Journal of Medical Ethics 39 (6):408-409.
Sven Ove Hansson (2006). Uncertainty and the Ethics of Clinical Trials. Theoretical Medicine and Bioethics 27 (2):149-167.
Maurie Markman (2004). The Research Misconception. International Journal of Applied Philosophy 18 (2):241-252.
R. Ashcroft (2002). What is Clinical Effectiveness? Studies in History and Philosophy of Science Part C 33 (2):219-233.
Margaret B. Liu (2010). A Clinical Trials Manual From the Duke Clinical Research Institute: Lessons From a Horse Named Jim. Wiley-Blackwell.
Roger Stanev (2011). Statistical Decisions and the Interim Analyses of Clinical Trials. Theoretical Medicine and Bioethics 32 (1):61-74.
Jeremy Howick, Against a Priori Judgements of Bad Methodology: Questioning Double-Blinding as a Universal Methodological Virtue of Clinical Trials.
Jeremy Howick (2011). The Philosophy of Evidence-Based Medicine. Wiley-Blackwell, Bmj Books.
Franklin G. Miller & Howard Brody (2002). What Makes Placebo-Controlled Trials Unethical? American Journal of Bioethics 2 (2):3 – 9.
Marek Czarkowski (2006). The Protection of Patients' Rights in Clinical Trials. Science and Engineering Ethics 12 (1):131-138.
Jennifer L. Gold & David M. Studdert (2005). Clinical Trials Registries: A Reform That is Past Due. Journal of Law, Medicine and Ethics 33 (4):811-820.
Danielle Laudy (2009). End of Life Pediatric Research: What About the Ethics? [REVIEW] Journal of Academic Ethics 7 (1-2):87-91.
Myriam Skrutkowska & Charles Weijer, Do Patients with Breast Cancer Participating in Clinical Trials Receive Better Nursing Care?
Added to index2010-08-24
Total downloads4 ( #243,847 of 1,096,600 )
Recent downloads (6 months)3 ( #99,452 of 1,096,600 )
How can I increase my downloads?