Homologous recombination promoted by Chi sites and RecBC enzyme of Escherichia coli

Bioessays 2 (6):244-249 (1985)
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Abstract

Chi sites are examples of special sites enhancing homologous recombination in their region of the chromosome. Chi, 5′ G‐C‐T‐G‐G‐T‐G‐G3′, is a recognition site for the RecBC enzyme, which nicks DNA near Chi as it unwinds DNA. A molecular model of genetic recombination incorporating these features is reviewed.

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