Conflicts of Interest in Clinical Practice and Research
David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
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Oxford University Press (1996)
Our society has long sanctioned, at least tacitly, a degree of conflict of interest in medical practice and clinical research as an unavoidable consequence of the different interests of the physician or clinical investigator, the patient or clinical research subject, third party payers or research sponsors, the government, and society as a whole, to name a few. In the past, resolution of these conflicts has been left to the conscience of the individual physician or clinical investigator and to professional organizations. The public is no longer willing to allow health care providers to wholly govern their own conflicts of interest for several reasons. These include: new forms of health care financing and delivery that provide innovative and lucrative opportunities for physician or insurer enrichment at patient expense; the increased importance of commercial research support as peer-reviewed governmental research support has decreased; evidence that physicians and clinical investigators too frequently resolve conflicts of interest in their own favor; and a general societal mistrust of authority. This volume represents a multidisciplinary effort, drawing from philosophy, medicine, law, economics and public policy to identify and categorize conflicts of interest in medical practice and clinical research, and, where possible, to offer a mechanism for resolving them. Part I addresses conflicts of interest from a theoretical perspective, offering basic concepts and analytical frameworks. The second part discusses two topics prominent in current health care policy debates--self-referral and financial incentives to limit care. Part III examines conflicts of interest generated by pharmaceutical industry involvement in clinical practice and research. The final section deals with conflicts of interest in clinical research in several contexts, including institutional reviews boards, clinical trials, Cooperative Research and Development Agreements between government and private researchers, brokerage of research subjects by Contract Research Organizations, and cost-effectiveness studies.
|Keywords||Medical ethics Conflict of interests Conflict of Interest Ethics, Medical Referral and Consultation Health Maintenance Organizations Research|
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|Call number||R724.C627 1996|
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David S. Shimm, R. G. Spece Jr & M. Burpeau DiGregorio, Conflicts of Interests in Relationships Between Physicians and the Pharmaceutical Industry.
Shimm & Spece, Discovering the Ethical Requirements of Physician Roles in the Service of Conflicting Interests as Healers and as Citizens.
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Laura Weiss Roberts & Timothy L. McAuliffe (2006). Investigators' Affirmation of Ethical, Safeguard, and Scientific Commitments in Human Research. Ethics and Behavior 16 (2):135 – 150.
Lance K. Stell (2009). Drug Reps Off Campus! Promoting Professional Purity by Suppressing Commercial Speech. Journal of Law, Medicine & Ethics 37 (3):431-443.
Lance K. Stell (2009). Drug Reps Off Campus! Promoting Professional Purity by Suppressing Commercial Speech. Journal of Law, Medicine and Ethics 37 (3):431-443.
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