With 'Genes' Like That, Who Needs an Environment? Postgenomics's Argument for the 'Ontogeny of Information'
David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Philosophy of Science 73 (5):905-917 (2006)
The linear sequence specification of a gene product is not provided by the target DNA sequence alone but by the mechanisms of gene expressions. The main actors of these mechanisms, proteins and functional RNAs, relay environmental information to the genome with important consequences to sequence selection and processing. This ‘postgenomic’ reality has implications for our understandings of development not as predetermined by genes but as an epigenetic process. Critics of genetic determinism have long argued that the activity of ‘genes’ and hence their contribution to the phenotype depends on intra- and extra-organismal ‘environmental’ elements. As will be shown here, even the mere physical existence of a ‘gene’ is dependent on its phenotypic context.
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
Eva Jablonka, Marion J. Lamb & Anna Zeligowski (2006). Evolution in Four Dimensions: Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life. A Bradford Book.
John S. Mattick (2003). Challenging the Dogma: The Hidden Layer of Non-Protein-Coding RNAs in Complex Organisms. Bioessays 25 (10):930-939.
Vincenzo Pirrotta (2002). Trans-Splicing inDrosophila. Bioessays 24 (11):988-991.
Citations of this work BETA
Ingo Brigandt (2010). The Epistemic Goal of a Concept: Accounting for the Rationality of Semantic Change and Variation. Synthese 177 (1):19-40.
David S. Moore (2008). Espousing Interactions and Fielding Reactions: Addressing Laypeople's Beliefs About Genetic Determinism. Philosophical Psychology 21 (3):331 – 348.
Ulrich E. Stegmann (2012). Varieties of Parity. Biology and Philosophy 27 (6):903-918.
Karola Stotz (2008). The Ingredients for a Postgenomic Synthesis of Nature and Nurture. Philosophical Psychology 21 (3):359 – 381.
Jeffrey H. Schwartz (2006). Decisions, Decisions: Why Thomas Hunt Morgan Was Not the "Father" of Evo-Devo. Philosophy of Science 73 (5):918-929.
Similar books and articles
Brant Pridmore (2008). Review of Genes in Development: Re-Reading the Molecular Paradigm. [REVIEW] Biology and Philosophy 23 (4):579-586.
Peter Godfrey-Smith (2007). Information in Biology. In David L. Hull & Michael Ruse (eds.), The Cambridge Companion to the Philosophy of Biology. Cambridge University Press. 103--119.
Tareq Syed, Michael Bölker & Mathias Gutmann (2008). Genetic “Information” or the Indomitability of a Persisting Scientific Metaphor. Poiesis and Praxis 5 (3-4):193-209.
Rosario M. Piro (2011). Are All Genes Regulatory Genes? Biology and Philosophy 26 (4):595-602.
Kim Sterelny, Kelly C. Smith & Michael Dickison (1996). The Extended Replicator. Biology and Philosophy 11 (3):377-403.
Holmes Rolston (2006). What is a Gene? From Molecules to Metaphysics. Theoretical Medicine and Bioethics 27 (6):471-497.
Petter Portin (2009). The Elusive Concept of the Gene. Hereditas 146 (3):112-117.
Karola Stotz (2006). With 'Genes' Like That, Who Needs an Environment? Postgenomics's Argument for the 'Ontogeny of Information'. Philosophy of Science 73 (5):905-917.
Added to index2009-01-28
Total downloads7 ( #191,580 of 1,099,682 )
Recent downloads (6 months)1 ( #301,057 of 1,099,682 )
How can I increase my downloads?