With 'Genes' Like That, Who Needs an Environment? Postgenomics's Argument for the 'Ontogeny of Information'
David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
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Philosophy of Science 73 (5):905-917 (2006)
The linear sequence specification of a gene product is not provided by the target DNA sequence alone but by the mechanisms of gene expressions. The main actors of these mechanisms, proteins and functional RNAs, relay environmental information to the genome with important consequences to sequence selection and processing. This ‘postgenomic’ reality has implications for our understandings of development not as predetermined by genes but as an epigenetic process. Critics of genetic determinism have long argued that the activity of ‘genes’ and hence their contribution to the phenotype depends on intra- and extra-organismal ‘environmental’ elements. As will be shown here, even the mere physical existence of a ‘gene’ is dependent on its phenotypic context.
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References found in this work BETA
Eva Jablonka, Marion J. Lamb & Anna Zeligowski (2006). Evolution in Four Dimensions: Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life. A Bradford Book.
John S. Mattick (2003). Challenging the Dogma: The Hidden Layer of Non-Protein-Coding RNAs in Complex Organisms. Bioessays 25 (10):930-939.
Vincenzo Pirrotta (2002). Trans-Splicing inDrosophila. Bioessays 24 (11):988-991.
Citations of this work BETA
Ingo Brigandt (2010). The Epistemic Goal of a Concept: Accounting for the Rationality of Semantic Change and Variation. Synthese 177 (1):19-40.
David S. Moore (2008). Espousing Interactions and Fielding Reactions: Addressing Laypeople's Beliefs About Genetic Determinism. Philosophical Psychology 21 (3):331 – 348.
Karola Stotz (2008). The Ingredients for a Postgenomic Synthesis of Nature and Nurture. Philosophical Psychology 21 (3):359 – 381.
Ulrich E. Stegmann (2012). Varieties of Parity. Biology and Philosophy 27 (6):903-918.
Jeffrey H. Schwartz (2006). Decisions, Decisions: Why Thomas Hunt Morgan Was Not the "Father" of Evo-Devo. Philosophy of Science 73 (5):918-929.
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