David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Ezio Di Nucci
Jack Alan Reynolds
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Kennedy Institute of Ethics Journal 15 (4):347-370 (2005)
: Experiments involving the transplantation of human stem cells and their derivatives into early fetal or embryonic nonhuman animals raise novel ethical issues due to their possible implications for enhancing the moral status of the chimeric individual. Although status-enhancing research is not necessarily objectionable from the perspective of the chimeric individual, there are grounds for objecting to it in the conditions in which it is likely to occur. Translating this ethical conclusion into a policy recommendation, however, is complicated by the fact that substantial empirical and ethical uncertainties remain about which transplants, if any, would significantly enhance the chimeric individual's moral status. Considerations of moral status justify either an early-termination policy on chimeric embryos, or, in the absence of such a policy, restrictions on the introduction of pluripotent human stem cells into early-stage developing animals, pending the resolution of those uncertainties
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Citations of this work BETA
Monika Piotrowska (2014). Transferring Morality to Human–Nonhuman Chimeras. American Journal of Bioethics 14 (2):4-12.
Henry T. Greely, Mildred K. Cho, Linda F. Hogle & Debra M. Satz (2007). Thinking About the Human Neuron Mouse. American Journal of Bioethics 7 (5):27 – 40.
Matthew H. Haber & Bryan Benham (2012). Reframing the Ethical Issues in Part-Human Animal Research: The Unbearable Ontology of Inexorable Moral Confusion. American Journal of Bioethics 12 (9):17-25.
Francoise Baylis (2008). Animal Eggs for Stem Cell Research: A Path Not Worth Taking. American Journal of Bioethics 8 (12):18-32.
P. S. Duggan, A. W. Siegel, D. M. Blass, H. Bok, J. T. Coyle, R. Faden, J. Finkel, J. D. Gearhart, H. T. Greely, A. Hillis, A. Hoke, R. Johnson, M. Johnston, J. Kahn, D. Kerr & P. King (2009). Unintended Changes in Cognition, Mood, and Behavior Arising From Cell-Based Interventions for Neurological Conditions: Ethical Challenges. American Journal of Bioethics 9 (5):31-36.
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