Using empirical data to inform the ethical evaluation of placebo controlled trials
Science and Engineering Ethics 10 (1) (2004)
| Abstract | There has been considerable debate about the ethical acceptability of using placebo-controls in clinical research. Although this debate has been rich in rhetoric, considering that much of this research is predicated upon the assumption that data from this research is vital to clinical decision-making, it is ironic that researchers have introduced little data into these discussions. Using some published research concerning the use of placebo-controls in clinical research in hypertension and psychiatric drug trials, I suggest some ways that such data might be incorporated into the ethical analysis concerning placebo use in clinical trials. This approach promises to be important for enhancing conceptual and scientific understanding as well as public policy decision-making. | |||||||||
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Joan Box (2004). Placebos and the UK Medical Research Council — and the Consumer Perspective. Science and Engineering Ethics 10 (1).
Gunnel Elander & Göran Hermerén (1995). Placebo Effect and Randomized Clinical Trials. Theoretical Medicine and Bioethics 16 (2).
James A. Anderson (2006). The Ethics and Science of Placebo-Controlled Trials: Assay Sensitivity and the Duhem-Quine Thesis. Journal of Medicine and Philosophy 31 (1):65 – 81.
Juhana E. Idänpään-Heikkilä & Sev Fluss (2004). The CIOMS View on the Use of Placebo in Clinical Trials. Science and Engineering Ethics 10 (1).
Thomas R. Weihrauch (2004). Placebo Treatment is Effective Differently in Different Diseases — but is It Also Harmless? A Brief Synopsis. Science and Engineering Ethics 10 (1).
Piotr Zaborowski & Adam Górski (2004). Informed Consent and the Use of Placebo in Poland: Ethical and Legal Aspects. Science and Engineering Ethics 10 (1).
Franklin G. Miller & Howard Brody (2002). What Makes Placebo-Controlled Trials Unethical? American Journal of Bioethics 2 (2):3 – 9.
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