David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Ezio Di Nucci
Jack Alan Reynolds
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Science and Engineering Ethics 10 (1):29-35 (2004)
There has been considerable debate about the ethical acceptability of using placebo-controls in clinical research. Although this debate has been rich in rhetoric, considering that much of this research is predicated upon the assumption that data from this research is vital to clinical decision-making, it is ironic that researchers have introduced little data into these discussions. Using some published research concerning the use of placebo-controls in clinical research in hypertension and psychiatric drug trials, I suggest some ways that such data might be incorporated into the ethical analysis concerning placebo use in clinical trials. This approach promises to be important for enhancing conceptual and scientific understanding as well as public policy decision-making.
|Keywords||placebos ethics research ethics clinical trials|
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References found in this work BETA
Benjamin Freedman, Kathleen Cranley Glass & Charles Weijer (1996). Placebo Orthodoxy in Clinical Research II: Ethical, Legal, and Regulatory Myths. Journal of Law, Medicine & Ethics 24 (3):252-259.
Benjamin Freedman, Charles Weijer & Kathleen Cranley Glass (1996). Placebo Orthodoxy in Clinical Research I: Empirical and Methodological Myths. Journal of Law, Medicine & Ethics 24 (3):243-251.
Citations of this work BETA
Paul Litton & Franklin G. Miller (2005). A Normative Justification for Distinguishing the Ethics of Clinical Research From the Ethics of Medical Care. Journal of Law, Medicine & Ethics 33 (Fall 2005):566-74.
Raymond E. Spier (2004). Placebo: Its Action and Place in Health Research Today* — Summary and Conclusions. Science and Engineering Ethics 10 (1):189-197.
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