David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
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Philosophy of Science 70 (2):235-254 (2003)
A biochemical pathway is a sequence of chemical reactions in a biological organism. Such pathways specify mechanisms that explain how cells carry out their major functions by means of molecules and reactions that produce regular changes. Many diseases can be explained by defects in pathways, and new treatments often involve finding drugs that correct those defects. This paper presents explanation schemas and treatment strategies that characterize how thinking about pathways contributes to biomedical discovery. It discusses the significance of pathways for understanding the nature of diseases, explanations, and theories.
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Citations of this work BETA
William Bechtel (2011). Mechanism and Biological Explanation. Philosophy of Science 78 (4):533-557.
Cory D. Wright (2012). Mechanistic Explanation Without the Ontic Conception. European Journal of Philosophy of Science 2 (3):375-394.
William Bechtel (2009). Looking Down, Around, and Up: Mechanistic Explanation in Psychology. Philosophical Psychology 22 (5):543-564.
Nicholaos Jones (2014). Bowtie Structures, Pathway Diagrams, and Topological Explanation. Erkenntnis 79 (5):1135-1155.
Dingmar van Eck (forthcoming). Reconciling Ontic and Epistemic Constraints on Mechanistic Explanation, Epistemically. Axiomathes 25 (1):5-22.
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