David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
Journal of Medical Ethics 31 (12):715-720 (2005)
Objective: The objective of the current study was to maximise the amount of information children and adolescents understand about the risks and benefits associated with participation in a biomedical research study.Design: Participants were presented with one of six hypothetical research protocols describing how to fix a fractured thigh using either a “standard” cast or “new” pins procedure. Risks and benefits associated with each of the treatment options were manipulated so that for each one of the six protocols there was either a correct or ambiguous choice.Participants and setting: Two hundred and fifty one children, ages 6–15 , and 237 adults were interviewed while waiting for a clinic appointment at the Hospital for Sick Children.Results: Using standardised procedures and questionnaires, it was determined that most participants, regardless of age group, were able to understand the basic purpose and procedures involved in the research, and most were able to choose the “correct” operation. The younger children, however, showed an overall preference for a cast operation, whereas the older participants were more likely to choose the pins.Conclusions: By creating age appropriate modules of information, children as young as six years can understand potentially difficult and complex concepts such as the risks and benefits associated with participation in biomedical research. It appears, however, that different criteria were used for treatment preference, regardless of associated risks; older participants tended to opt for mobility whereas younger participants stayed with the more familiar cast operation
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
No references found.
Citations of this work BETA
Marcin Waligora, Vilius Dranseika & Jan Piasecki (2014). Child's Assent in Research: Age Threshold or Personalisation? BMC Medical Ethics 15 (1):44.
Similar books and articles
Rona Abramovitch, Jonathan L. Freedman, Kate Henry & Michelle Van Brunschot (1995). Children's Capacity to Agree to Psychological Research: Knowledge of Risks and Benefits and Voluntariness. Ethics and Behavior 5 (1):25 – 48.
Janet Malek (2007). Understanding Risks and Benefits in Research on Reproductive Genetic Technologies. Journal of Medicine and Philosophy 32 (4):339 – 358.
Alexander Friedman, Emily Robbins & David Wendler (2012). Which Benefits of Research Participation Count as 'Direct'? Bioethics 26 (2):60-67.
David Wendler (2012). A New Justification for Pediatric Research Without the Potential for Clinical Benefit. American Journal of Bioethics 12 (1):23 - 31.
Annette Rid & David Wendler (2011). A Framework for Risk-Benefit Evaluations in Biomedical Research. Kennedy Institute of Ethics Journal 21 (2):141-179.
Charles Weijer & Paul B. Miller (2007). Refuting the Net Risks Test: A Response to Wendler and Miller's "Assessing Research Risks Systematically". Journal of Medical Ethics 33 (8):487-490.
Charles Weijer & Paul B. Miller, When Are Research Risks Reasonable in Relation to Anticipated Benefits?
Georg Spielthenner (2012). Risk-Benefit Analysis: From a Logical Point of View. [REVIEW] Journal of Bioethical Inquiry 9 (2):161-170.
John Appiah-Poku, Sam Newton & Nancy Kass (2011). Participants' Perceptions of Research Benefits in an African Genetic Epidemiology Study. Developing World Bioethics 11 (3):128-135.
David Wendler (2005). Protecting Subjects Who Cannot Give Consent: Toward a Better Standard for "Minimal" Risks. Hastings Center Report 35 (5):37-43.
Johanna Dwyer & Franklin M. Loew (1994). Nutritional Risks of Vegan Diets to Women and Children: Are They Preventable? [REVIEW] Journal of Agricultural and Environmental Ethics 7 (1):87-109.
Charles Weijer, The Ethical Analysis of Risks and Potential Benefits in Human Subjects Research: History, Theory, and Implications for U.S. Regulation.
Sven Ove Hansson (2004). Weighing Risks and Benefits. Topoi 23 (2):145-152.
Angela Ballantyne (2008). Benefits to Research Subjects in International Trials: Do They Reduce Exploitation or Increase Undue Inducement? Developing World Bioethics 8 (3):178-191.
Added to index2010-08-24
Total downloads5 ( #359,709 of 1,725,584 )
Recent downloads (6 months)2 ( #268,753 of 1,725,584 )
How can I increase my downloads?