Evolutionary medicine at twenty: rethinking adaptationism and disease [Book Review]

Biology and Philosophy 27 (2):241-261 (2012)
Abstract
Two decades ago, the eminent evolutionary biologist George C. Williams and his physician coauthor, Randolph Nesse, formulated the evolutionary medicine research program. Williams and Nesse explicitly made adaptationism a core component of the new program, which has served to undermine the program ever since, distorting its practitioners’ perceptions of evidentiary burdens and in extreme cases has served to warp practitioner’s understandings of the relationship between evolutionary benefits/detriments and medical ones. I show that the Williams and Nesse program more particularly embraces the panselectionist variety of adaptationism (the empirical assumption that non-adaptive evolutionary processes are causally unimportant compared to natural selection), and argue that this has harmed the field. Panselectionism serves to conceal the enormous evidentiary hurdles that evolutionary medicine hypotheses face, making them appear stronger than they are. I use two examples of evolutionary medicine texts, on neonatal jaundice and on asthma, to show that some evolutionary medicine practitioners have allowed their fervent panselectionism to directly shape their recommendations for clinical practice. I argue that this escalation of panselectionism’s influence is inappropriate under Williams’ and Nesse original stated standards, despite being inspired by their program. I also show that the examples’ conflation of clinical and evolutionary considerations is inappropriate even under Christopher Boorse’s controversial evolution-rooted concepts of disease and health
Keywords Adaptationism  Biostatistical theory  Darwinian medicine  Evolutionary medicine  Maladaptation  Panselectionism
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References found in this work BETA
Jonathan Kaplan (2002). Historical Evidence and Human Adaptations. Proceedings of the Philosophy of Science Association 2002 (3):S294-S304.

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Anne Gammelgaard (2000). Evolutionary Biology and the Concept of Disease. Medicine, Health Care and Philosophy 3 (2):109-116.
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