Inference to the best manipulation – a case study of qualitative reasoning in neuropharmacy

Foundations of Science 4 (4):483-495 (1999)
How can new drug lead suggestions beinferred from neurophysiological models? This paperaddresses this question based on a case study ofresearch into Parkinson''s disease at the GroningenUniversity Department of Pharmacy. It is argued thatneurophysiological box-and-arrow models can beunderstood as qualitative differential equationmodels. An inference task is defined to helpunderstand and possibly aid the discovery andexplanation of new drug lead suggestions.
Keywords discovery  drug lead  pharmacy  philosophy of medicine  qualitative reasoning
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DOI 10.1023/A:1009652019363
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