The human genome project: Towards an analysis of the empirical, ethical, and conceptual issues involved [Book Review]
David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
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Biology and Philosophy 7 (3):255-278 (1992)
In this paper I claim that the goal of mapping and sequencing the human genome is not wholly new, but rather is an extension of an older project to map genes, a central aim of genetics since its birth. Thus, the discussion about the value of the HGP should not be posed in global terms of acceptance or rejection, but in terms of how it should be developed. The first section of this paper presents a brief history of the project. The second section distinguishes among four kinds of issues relevant to an evaluation of the HGP: those economic and organizational issues related to the feasibility of the project; the ethical questions arising in the development of the project and the application of the data gathered; the empirical issues relevant to the scientific value of the project; and conceptual issues like reductionism and determinism relevant to understand the nature and scope of the project. In a third section, I analyze in detail whether the HGP and, more generally, molecular biology is reductionistic.
|Keywords||Human Genome Project molecular biology reductionism|
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References found in this work BETA
F. Ayala & T. Dobzhansky (eds.) (1974). Studies in the Philosophy of Biology. University of California Press.
John Beatty (1982). The Insights and Oversights of Molecular Genetics: The Place of the Evolutionary Perspective. PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1982:341 - 355.
J. A. Fodor (1974). Special Sciences (Or: The Disunity of Science as a Working Hypothesis). Synthese 28 (2):97-115.
William K. Goosens (1978). Reduction by Molecular Genetics. Philosophy of Science 45 (1):73-95.
Santiago Grisolia (1989). Mapping the Human Genome. Hastings Center Report 19 (4):18-19.
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