Cancer as a mechanism of hypermutation
Acta Biotheoretica 40 (1) (1992)
| Abstract | The highly structured mechanisms of cancers, their tendency to occur as a response to environmental stress, and the existence of oncogenes, suggest that neoplasticity may represent more than a biological disfunction. It is proposed that cancer exists as a phylogenetic mechanism serving to promote hyperevolution, albeit at the expense of the ontogeny, that is similar to a process recently discovered in bacterial mutations. Cell-surface-associated nucleic acid in tumorigenic cells and sperm cell vectorization of foreign DNA indicate the existence of essential mechanisms necessary to the occurrence of cancer mediated hyperevolution. An analysis of the proposed mechanism indicates that for mutagenesis of chemical cytology, stress induced neoplasticity confers an evolutionary advantage of more than two orders of magnitude. | |||||||||
| Keywords | No keywords specified (fix it) | |||||||||
| Categories | ||||||||||
| Options |
|
|||||||||
Download options| PhilPapers Archive |
Upload a copy of this paper Check publisher's policy on self-archival Papers currently archived: 5,679 |
| External links |
 |
| Through your library | Configure |
Similar books and articlesJames A. Marcum (2005). Metaphysical Presuppositions and Scientific Practices: Reductionism and Organicism in Cancer Research. International Studies in the Philosophy of Science 19 (1):31 – 45.
Bartlomiej Swiatczak (2011). Indeterminism in the Immune System: The Case of Somatic Hypermutation. Paradigmi 1:49-65.
Philip Hahnfeldt (forthcoming). Quantitative Modeling of Tumor Dynamics and Radiotherapy. Acta Biotheoretica.
Rebecca Dresser (2011). Bioethics and Cancer: When the Professional Becomes Personal. Hastings Center Report 41 (6):14-18.
Armando Aranda-Anzaldo (2001). Cancer Development and Progression: A Non-Adaptive Process Driven by Genetic Drift. Acta Biotheoretica 49 (2).
Knut Borch-Johnsen, Jørgen H. Olsen & Thorkild I. A. Sørensen (1994). Genes and Family Environment in Familial Clustering of Cancer. Theoretical Medicine and Bioethics 15 (4).
Deng K. Niu & Jia-Kuan Chen (1998). Ideas in Theoretical Biology Origin of Cancerous Cells From Tumours. Acta Biotheoretica 46 (4).
Susan Gilbert (2010). Personalized Cancer Care in an Age of Anxiety. Hastings Center Report 40 (5):18-21.
Analytics
Monthly downloads
Sorry, there are not enough data points to plot this chart.
|
Added to index2009-01-28Total downloads1 ( #274,830 of 549,087 )Recent downloads (6 months)0How can I increase my downloads? |
My notes
Discussion
