Sham neurosurgery in patients with Parkinson's disease: is it morally acceptable?

Journal of Medical Ethics 27 (3):151-156 (2001)
For a few decades, patients with Parkinson's disease have been treated with intracerebral transplantations of fetal mesencephalic tissue. The results of open trials have been variable. Double blind, placebo-controlled studies have recently been started in order to further investigate the efficacy of this new medical technique. In this paper we challenge the need for sham surgery in neurotransplantation research on PD patients. Considerations regarding the research subjects' informed consent, therapeutic misconception, the integrity of the human body, and the assessment of risks and benefits argue against sham surgery for patients with PD. Moreover, there is an alternative, less harmful mode of research that can provide the same or comparable scientific evidence. A plea is made for intrapatient research based on quantitative measurements of the patient's pre- and post-operative condition combined with similar research on a reference group of patients who have received the standard treatment
Keywords No keywords specified (fix it)
Categories (categorize this paper)
DOI 10.1136/jme.27.3.151
 Save to my reading list
Follow the author(s)
My bibliography
Export citation
Find it on Scholar
Edit this record
Mark as duplicate
Revision history Request removal from index
Download options
PhilPapers Archive

Upload a copy of this paper     Check publisher's policy on self-archival     Papers currently archived: 15,879
External links
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library
References found in this work BETA

No references found.

Add more references

Citations of this work BETA
Franklin G. Miller (2004). Sham Surgery: An Ethical Analysis. Science and Engineering Ethics 10 (1):41-48.

Add more citations

Similar books and articles
den Bosch & M. P. (2005). Structures in Neuropharmacology. Poznan Studies in the Philosophy of the Sciences and the Humanities 84 (1):343-359.
Franklin G. Miller (2004). Sham Surgery: An Ethical Analysis. Science and Engineering Ethics 10 (1):41-48.
Irwin Savodnik (2002). The Disease Status of Catatonia. Behavioral and Brain Sciences 25 (5):590-591.
Walter Glannon (1998). Responsibility, Alcoholism, and Liver Transplantation. Journal of Medicine and Philosophy 23 (1):31 – 49.

Monthly downloads

Added to index


Total downloads

4 ( #404,953 of 1,725,161 )

Recent downloads (6 months)

1 ( #349,161 of 1,725,161 )

How can I increase my downloads?

My notes
Sign in to use this feature

Start a new thread
There  are no threads in this forum
Nothing in this forum yet.