The crux of crucial experiments: Duhem's problems and inference to the best explanation

Abstract
Going back at least to Duhem, there is a tradition of thinking that crucial experiments are impossible in science. I analyse Duhem's arguments and show that they are based on the excessively strong assumption that only deductive reasoning is permissible in experimental science. This opens the possibility that some principle of inductive inference could provide a sufficient reason for preferring one among a group of hypotheses on the basis of an appropriately controlled experiment. To be sure, there are analogues to Duhem's problems that pertain to inductive inference. Using a famous experiment from the history of molecular biology as an example, I show that an experimentalist version of inference to the best explanation (IBE) does a better job in handling these problems than other accounts of scientific inference. Furthermore, I introduce a concept of experimental mechanism and show that it can guide inferences from data within an IBE-based framework for induction. Introduction Duhem on the Logic of Crucial Experiments ‘The Most Beautiful Experiment in Biology’ Why Not Simple Elimination? Severe Testing An Experimentalist Version of IBE 6.1 Physiological and experimental mechanisms 6.2 Explaining the data 6.3 IBE and the problem of untested auxiliaries 6.4 IBE-turtles all the way down Van Fraassen's ‘Bad Lot’ Argument IBE and Bayesianism Conclusions CiteULike Connotea Del.icio.us What's this?
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References found in this work BETA
S. Okasha (2000). Van Fraassen's Critique of Inference to the Best Explanation. Studies in History and Philosophy of Science Part A 31 (4):691-710.
Citations of this work BETA
Tudor M. Baetu (2014). Models and the Mosaic of Scientific Knowledge. The Case of Immunology. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 45:49-56.
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