David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
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American Journal of Bioethics 12 (1):23 - 31 (2012)
Pediatric research without the potential for clinical benefit is vital to improving pediatric medical care. This research also raises ethical concern and is regarded by courts and commentators as unethical. While at least 10 justifications have been proposed in response, all have fundamental limitations. This article describes and defends a new justification based on the fact that enrollment in clinical research offers children the opportunity to contribute to a valuable project. Contributing as children to valuable projects can benefit individuals in two ways. First, individuals may come to ?embrace? the contributions they made as children. Second, contributing to valuable projects can lead to a better overall life. Because these potential benefits can outweigh small research risks, they provide a justification for pediatric research without the potential for clinical benefit, when it poses low risks and has the potential to benefit others in important ways
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References found in this work BETA
Terrence F. Ackerman (1980). Moral Duties of Parents and Nontherapeutic Clinical Research Procedures Involving Children. Bioethics Quarterly 2 (2):94-111.
Jeremy Bentham (1780/2007). An Introduction to the Principles of Morals and Legislation. Dover Publications.
Benjamin Freedman, Abraham Fuks & Charles Weijer (1993). In Loco Parentis: Minimal Risk as an Ethical Threshold for Research Upon Children. Hastings Center Report 23 (2):13-19.
Loretta M. Kopelman (2004). Minimal Risk as an International Ethical Standard in Research. Journal of Medicine and Philosophy 29 (3):351 – 378.
C. Lenk (2004). Non-Therapeutic Research with Minors: How Do Chairpersons of German Research Ethics Committees Decide? Journal of Medical Ethics 30 (1):85-87.
Citations of this work BETA
Loretta M. Kopelman (2012). On Justifying Pediatric Research Without the Prospect of Clinical Benefit. American Journal of Bioethics 12 (1):32 - 34.
Silvia Camporesi & Matteo Mameli (2012). The Context of Clinical Research and Its Ethical Relevance: The COMPAS Trial as a Case Study. American Journal of Bioethics 12 (1):39 - 40.
David Hunter (2012). Why Even Inappropriate Parental Consent Might Be Enough to Justify Minimal Risk Pediatric Research Without Clinical Benefit. American Journal of Bioethics 12 (1):35 - 36.
Carlo Petrini (2012). Consent to Pediatric Research: A Couple of Distinctions. American Journal of Bioethics 12 (1):37 - 38.
Paul Litton (2012). A More Persuasive Justification for Pediatric Research. American Journal of Bioethics 12 (1):44 - 46.
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