David Bourget (Western Ontario)
David Chalmers (ANU, NYU)
Rafael De Clercq
Jack Alan Reynolds
Learn more about PhilPapers
American Journal of Bioethics 12 (1):23 - 31 (2012)
Pediatric research without the potential for clinical benefit is vital to improving pediatric medical care. This research also raises ethical concern and is regarded by courts and commentators as unethical. While at least 10 justifications have been proposed in response, all have fundamental limitations. This article describes and defends a new justification based on the fact that enrollment in clinical research offers children the opportunity to contribute to a valuable project. Contributing as children to valuable projects can benefit individuals in two ways. First, individuals may come to ?embrace? the contributions they made as children. Second, contributing to valuable projects can lead to a better overall life. Because these potential benefits can outweigh small research risks, they provide a justification for pediatric research without the potential for clinical benefit, when it poses low risks and has the potential to benefit others in important ways
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
|Through your library|
References found in this work BETA
Terrence F. Ackerman (1980). Moral Duties of Parents and Nontherapeutic Clinical Research Procedures Involving Children. Bioethics Quarterly 2 (2):94-111.
Jeremy Bentham (1780/2007). An Introduction to the Principles of Morals and Legislation. Dover Publications.
Benjamin Freedman, Abraham Fuks & Charles Weijer (1993). In Loco Parentis: Minimal Risk as an Ethical Threshold for Research Upon Children. Hastings Center Report 23 (2):13-19.
Loretta M. Kopelman (2004). Minimal Risk as an International Ethical Standard in Research. Journal of Medicine and Philosophy 29 (3):351 – 378.
C. Lenk (2004). Non-Therapeutic Research with Minors: How Do Chairpersons of German Research Ethics Committees Decide? Journal of Medical Ethics 30 (1):85-87.
Citations of this work BETA
Loretta M. Kopelman (2012). On Justifying Pediatric Research Without the Prospect of Clinical Benefit. American Journal of Bioethics 12 (1):32 - 34.
Silvia Camporesi & Matteo Mameli (2012). The Context of Clinical Research and Its Ethical Relevance: The COMPAS Trial as a Case Study. American Journal of Bioethics 12 (1):39 - 40.
David Hunter (2012). Why Even Inappropriate Parental Consent Might Be Enough to Justify Minimal Risk Pediatric Research Without Clinical Benefit. American Journal of Bioethics 12 (1):35 - 36.
Carlo Petrini (2012). Consent to Pediatric Research: A Couple of Distinctions. American Journal of Bioethics 12 (1):37 - 38.
Paul Litton (2012). A More Persuasive Justification for Pediatric Research. American Journal of Bioethics 12 (1):44 - 46.
Similar books and articles
Paul Litton, Non-Beneficial Pediatric Research and the Best Interests Standard: A Legal and Ethical Reconciliation.
Andrew D. McRae & Charles Weijer, Lessons From Everyday Lives: A Moral Justification for Acute Care Research.
David Wendler & Christine Grady (2008). What Should Research Participants Understand to Understand They Are Participants in Research? Bioethics 22 (4):203–208.
Danielle Laudy (2009). End of Life Pediatric Research: What About the Ethics? [REVIEW] Journal of Academic Ethics 7 (1-2):87-91.
Alexander Friedman, Emily Robbins & David Wendler (2012). Which Benefits of Research Participation Count as 'Direct'? Bioethics 26 (2):60-67.
Eric Chwang (2010). Against Risk-Benefit Review of Prisoner Research. Bioethics 24 (1):14-22.
David Wendler & Emily Abdoler (2011). Does It Matter Whether Investigators Intend to Benefit Research Subjects? Kennedy Institute of Ethics Journal 20 (4):353-370.
Annette Rid & David Wendler (2011). A Framework for Risk-Benefit Evaluations in Biomedical Research. Kennedy Institute of Ethics Journal 21 (2):141-179.
Charles Weijer & Paul B. Miller (2007). Refuting the Net Risks Test: A Response to Wendler and Miller's "Assessing Research Risks Systematically". Journal of Medical Ethics 33 (8):487-490.
Howard Kunin (1997). Ethical Issues in Pediatric Life-Threatening Illness: Dilemmas of Consent, Assent, and Communication. Ethics and Behavior 7 (1):43 – 57.
Jacquelyn Slomka (2009). Manufacturing Mistrust: Issues in the Controversy Regarding Foster Children in the Pediatric Hiv/Aids Clinical Trials. Science and Engineering Ethics 15 (4):503-516.
Gillian Nycum & Lynette Reid (2007). The Harm-Benefit Tradeoff in "Bad Deal" Trials. Kennedy Institute of Ethics Journal 17 (4):321-350.
Jérémy Vanhelst, Ludovic Hardy, Dina Bert, Stéphane Duhem, Stéphanie Coopman, Christian Libersa, Dominique Deplanque, Frédéric Gottrand & Laurent Béghin (2013). Effect of Child Health Status on Parents' Allowing Children to Participate in Pediatric Research. BMC Medical Ethics 14 (1):7.
Kenneth V. Iserson (2007). Has Emergency Medicine Research Benefited Patients? An Ethical Question. Science and Engineering Ethics 13 (3):289-295.
David Wendler (2004). Risk Standards for Pediatric Research: Rethinking The. Kennedy Institute of Ethics Journal 14 (2):187-198.
Added to index2012-01-07
Total downloads16 ( #113,476 of 1,413,175 )
Recent downloads (6 months)1 ( #153,719 of 1,413,175 )
How can I increase my downloads?