Let’s suppose that the Axial Period is a time in history that is a transition between the first time of the temporal subject and the second time of the temporal subject; that it is the second stage of meaning: a troubled time between a first stage of meaning, characterized by a spontaneously operative consciousness in ‘early’ culture, and a third stage of meaning constituted by at least a dominant authority of a luminous control of meaning and an explicit (...) metaphysics in a ‘later’ global culture. What this statement means we have now to uncover. (shrink)

The concept of the axial age, initially proposed by the philosopher Karl Jaspers to refer to a period in the first millennium BCE that saw the rise of major religious and philosophical figures and ideas throughout Eurasia, has gained an established position in a number of fields, including historical sociology, cultural sociology, and the sociology of religion. We explore whether the notion of an “axial age” has historical and intellectual cogency, or whether the authors who use the (...) label of a more free-floating “axiality” to connote varied “breakthroughs” in human experience may have a more compelling case. Throughout, we draw attention to ways in which uses of the axial age concept in contemporary social science vary in these and other respects. In the conclusion, we reflect on the value of the concept and its current uses and their utility in making sense of human experience. (shrink)

The revolutionary outbreak in a variety of civilizations centered around 600 B.C.E., a period in which the great world religions as well as philosophy emerged, from Hebrew scriptures and the teachings of Buddha to the works of Greek and Chinese philosophers, has been named the Axial Age by Karl Jaspers. Yet 75 years earlier, in 1873, unknown to Jaspers and still unknown to the world, John Stuart Stuart-Glennie elaborated a fully developed and more nuanced theory of what he (...) termed The Moral Revolution to characterize the period. This book also brings to light the previously undiscussed ideas of D. H. Lawrence on the phenomenon from 20 years before Jaspers, the seldom mentioned contributions of Lewis Mumford, and proposes a new context for understanding the phenomenon. Halton rewrites the history of this fascinating theory and opens new ways of conceiving the meaning of The Moral Revolution for today. (shrink)

Religious Evolution and the Axial Age describes and explains the evolution of religion over the past ten millennia. It shows that an overall evolutionary sequence can be observed, running from the spirit and shaman dominated religions of small-scale societies, to the archaic religions of the ancient civilizations, and then to the salvation religions of the Axial Age. Stephen K. Sanderson draws on ideas from new cognitive and evolutionary psychological theories, as well as comparative religion, anthropology, history, and sociology. (...) He argues that religion is a biological adaptation that evolved in order to solve a number of human problems, especially those concerned with existential anxiety and ontological insecurity. Much of the focus of the book is on the Axial Age, the period in the second half of the first millennium BCE that marked the greatest religious transformation in world history. The book demonstrates that, as a result of massive increases in the scale and scope of war and large-scale urbanization, the problems of existential anxiety and ontological insecurity became particularly acute. These changes evoked new religious needs, especially for salvation and release from suffering. As a result entirely new religions-Zoroastrianism, Judaism, Christianity, Hinduism, Buddhism, Confucianism, and Daoism-arose to help people cope with the demands of the new historical era. (shrink)

How should we think about the “shape” of human history since the birth of cities, and where are we headed? Sociologist and historian John Torpey proposes that the “Axial Age” of the first millennium BCE, when some of the world’s major religious and intellectual developments first emerged, was only one of three such decisive periods that can be used to directly affect present social problems, from economic inequality to ecological destruction. Torpey’s argument advances the idea that there are in (...) fact three “Axial Ages,” instead of one original Axial Age and several subsequent, smaller developments. Each of the three ages contributed decisively to how humanity lives, and the difficulties it faces. The earliest, or original, Axial Age was a moral one; the second was material, and revolved around the creation and use of physical objects; and the third is chiefly mental, and focused on the technological. While there are profound risks and challenges, Torpey shows how a worldview that combines the strengths of all three ages has the potential to usher in a period of exceptional human freedom and possibility. (shrink)

This article argues that Karl Jaspers’s account of the rise of the Axial Age phenomenon is deficient owing to his failure to consider the natural law as a plausible cause for its development. The Axial Age concept—which precedes Jaspers, who nevertheless popularized it—claims that widely separated civilizations from the Ancient Greeks and Hebrews to the Persian, Hindu, Buddhist, and Confucian cultures all began to display sophisticated political and moral development from 800–200 BC, without any known contact. Jaspers regarded (...) its rise as a mystery. However, given ancient legal codes containing moral precepts long predating this period, the natural law hypothesis serves as the most plausible explanation of this ‘mystery’ of mankind’s dawning moral awareness. (shrink)

While post-modernist assaults on modernity correctly expose the pretensions of modernity – including its constructs of meaning in history, its abnegation of mystery, and its lapses into scientism, historicism, and relativism – the philosopher and theologian Bernard Lonergan discerned progress as well as decline in recent intellectual history. In part this is because under contemporary conditions we can avoid the pretensions of modernity, since – in the wake of modern science and modern historical scholarship – we witness the differentiation of (...) interiority, which, properly understood as the discovery of the self, may be seen as leading to a new integration of the spiritual, the intellectual, the moral, and the historical. (shrink)

The rise and legacy of world religions out of that period centered roughly around 500-600 BCE, what John Stuart-Glennie termed in 1873 the moral revolution, and Karl Jaspers later, in 1949, called the axial age, has been marked by heightened ideas of transcendence. Yet ironically, the world itself, in the literal sense of the actual earth, took on a diminished role as a central element of religious sensibility in the world religions, particularly in the Abrahamic religions. Given the (...) issue today of ecological unsustainability, including massive die-offs of wildlife and ever-increasing global human population and consumption, the legacy of those world religions face the question I consider here: Can religion transcend the earth in the long run? With the Axial Age/Moral Revolution, comes the possibility of transcendence of the world per se. The moral revolution/Axial Age represented significant changes in civilization, to be sure, but it can also be taken, as I do, as a second phase in the radical shift to anthropocentric mind already begun with the advent of agriculturally based civilization. The axial ideal of transcendence connects to a larger ideal, manifest not only in the legacies of the world religions but in contemporary science and technology, of a philosophy of escape from the earth. I show how ideas of axial transcendence, celebrated by scholars such as Jaspers and Bellah, nevertheless involve an unacknowledged tragic cost, the forgetting of the earth and its lessons and limits as central to what I have termed elsewhere, “sustainable wisdom.” . (shrink)

IntroductionDeep brain stimulation is an effective treatment for advanced Parkinson’s disease with the targeting bilateral subthalamic nucleus or globus pallidus internus. So far, detailed studies on the efficacy of unilateral STN-DBS for motor symptoms have been reported, but few studies have been conducted on unilateral GPi-DBS.Materials and MethodsSeventeen patients with Parkinson’s disease who underwent unilateral GPi-DBS were selected. We conducted comparison analyses between scores obtained 6–42 months pre- and postoperatively using the following measurement tools: the Movement Disorder Society Unified Parkinson’s (...) Disease Rating Scale part III, the Hoehn and Yahr stage, the presence/absence of dyskinesia, Mini-Mental State Examination, Frontal Assessment Battery, Geriatric Depression Scale, levodopa equivalent dose, and cerebral blood flow by single photon emission computed tomography. Patient backgrounds were compared between four cohorts with favorable and unfavorable postoperative outcome.ResultsSignificant improvement was observed postoperatively in the following: total MDS-UPDRS Part III scores during the off period, contralateral scores, ipsilateral scores, and axial scores. Similarly, the Hoehn and Yahr stages during the off period, and GDS also showed significant decrease. In contrast, LED, MMSE, and FAB remained unchanged while the number of patients who scored positive for dyskinesia decreased by 40%. Abnormal cerebral blood flow preoperatively seen in the cerebral cortex had normalized in the total score-based good responder cohort. In the ipsilateral score-based good responder cohort, cerebral blood flow increased in the contralateral frontal lobe including in the premotor cortex, contralateral to the DBS. Compared to the poor responders, postoperative good responders demonstrated significantly higher preoperative MMSE scores.DiscussionUnilateral GPi-DBS therapy was effective in improving contralateral, ipsilateral, and axial motor symptoms of patients with advanced PD; in particular, it was found to be especially beneficial in PwPD whose cognitive function was unimpaired; the treatment efficacy rivaled that of bilateral counterparts up till at least 6 months postoperatively. Finally, normalization of preoperative abnormalities in cerebral blood flow and increased cerebral blood flow in the contralateral frontal lobe indicated the beneficial potential of this therapy on ipsilateral motor symptoms. (shrink)

This article describes a challenge to the cultures and religions of the world that the author believes is the greatest challenge that has confronted the human race in its entire history. Modernity's search for unity and postmodernity's affirmation of pluralism reflect aspects of our current situation, but more needs to be recognized. We must acknowledge that East and West must face the current challenges together. Multiculturalism and unity encompass all world cultures, and we cannot be content to read our present (...) history only through the lens of western developments. Karl Jaspers's theory of the First Axial period of history, 800‐200 B.C.E., in which all the present world religions have their roots, is useful. It reveals that our present flowering of culture and spirit in the Western world, including our science, is not so much a product of the Western Renaissance and Enlightenment, as it is rooted in cultural events that belong to East and West equally. We are now in the Second Axial Period, which challenges the world religions to allow their energies to move toward convergence, just as in the previous millennia they moved toward differentiation. Teilhard de Chardin's thought is a guide for us, in his vision of a complex convergence of consciousness, in which differences will not be abolished but will be transformed in their coming together. This convergent perspective will also join with the perspective of rediscovering our roots in the earth, and it will repossess the spirituality of the primal peoples, in its understanding of the entire human race to be one tribe. The world religions are faced with the task, therefore, of encountering each other in “dialogic dialogue,” and channeling their spiritual resources toward the solution of real‐world global problems. (shrink)

The period 800–200 B.C.E. has been called an axial period or age because it was a period of major technological and cultural change that led to the development of new worldviews, which in turn called for and led to the emergence of the current major world religious traditions. The world is now in the midst of another period of major global scientific, technological, and cultural change that is leading to the development of a new global (...) worldview. In this worldview, the cosmos is taken to be more like an activity than a thing—more like an emergent complex of interrelated and interactive doing in space–time than a created complex of beings in space and time–and its complexity and space—time scale are understood to be enormously greater than heretofore supposed.These changes in worldview call for changes in theology, religion, and ethics. Most workers in the field of science and religion are heeding this call by attempting to reconcile traditional religious concepts with the new scientific concepts. Others, however, have become convinced that the new worldview differs so radically from the previous ones as to mark a new axial age, which calls for a new, post‐traditional theology, religion, and ethics, with a theos that is more like an activator of doing than a ground of being, and with meaning and purpose achieved more by a quality of doing than a quantity or quality of being. (shrink)

The article concerns history, its origins, goals, and end. The article focuses on two concepts of historical development. One is the concept of the “end of history” by Francis Fukuyama. The article’s authors consider in detail the main provisions of this concept. However, the main emphasis is on the critical reception of this concept within the framework of the philosophy of liberation (represented by Arturo Andrés Roig). Roig’s criticism reveals the Eurocentrism inherent in this concept and shows that it carries (...) the main features inherent in the European worldview and European mentality, which is why it is initially perceived as unsuitable for the Latin American continent. The second concept of historical development analyzed in this article is the earlier concept of the “Axial Age” by K. Jaspers. This concept is often perceived as one of the most striking anti-Eurocentric concepts. At the same time, Jaspers himself is regarded as the founder of the dialogue of cultures and intercultural philosophy and a supporter of civilizational pluralism. The article consistently analyzes three aspects of this concept - the motivation for its creation (presented by Jaspers himself), the criteria for identifying historical and prehistoric cultures (and the associated identification of three centers of the axial period), and the question of the possibility of a new axial age. The article argues that Jaspers’ concept can rightly be called Eurocentric rather than anti-Eurocentric, since both in the initial motivation for creating this concept and in the process of its development and vision of the prospects for the possibility of a new axial age, Jaspers proceeds from the presuppositions characteristic of the European worldview, which is universalized by him and presented as objective and the only correct ones. Ultimately, the study shows that the fight against Eurocentrism is a logical continuation of the latter and carries all the main features of the European mentality. (shrink)

The paper continues the model I began in a previous issue of Sophia . It is argued that the predominance of purely ascending or ‘top down’ forms of spirituality which stemmed largely from the axial period and have been carried forward into modern, transpersonal theories of evolutionary spirituality is a mistake and that there exists a lost or largely ignored form of spirituality—which I name somatic—which was the predominant domain of early Neolithic and Palaeolithic experience. Aspects of what (...) I call somatic mystical experiences have certainly been acknowledged at times to a limited degree, though they have rarely been fully explored, and have usually been considered as basic to other kinds of mystical experience, rather than fully developed forms in their own right. This article offers a fuller exploration and places such states more accurately within a detailed developmental framework than has previously been the case. Other issues relating to the horizon model across the two papers are also expanded. (shrink)

This volume is a study of the influence of Timaeus on the development of Western cosmology in three axial periods of European culture: Late Antiquity, Middle Ages and Renaissance.

When it comes to God-language, we must speak symbolically rather than literally. God’s unsearchable mystery requires that we address God only via multi-valent symbols that both connect us with God yet protect God from total disclosure. During the axial period 2500 years ago we learned that symbols resonate at the intersection of the beyond and the intimate, the transcendent and the immanent, the ultimate and the mundane. In Martin Luther’s Theology of the Cross we learned that God can (...) even be revealed under the opposite—that is, eternal life is revealed under temporal death. (shrink)

To grasp the truth in traditional Chinese classics, we need to uncover the long obscured "xiang" 象 (image) thinking, which has long been overshadowed by Occidentalism, "xiang thinking" is the most fundamental thought of human beings. The logic of linguistics all comes from "xiang thinking". Through conceptual thinking, people can understand Western classics on metaphysics, yet they may not completely understand the various schools of Chinese classics. The difference between Chinese and Western ways of thinking originated in the difference of (...) the basic views developed in the "Axial period". Since Aristotle, Western metaphysical ideas have all been manifested in substantiality, objectivity, and being ready-made, whereas Chinese Taiji, Dao, Xin-xing, and Zen were manifested in the non-substantiality, non-objectivity, and non-ready-made-ness of a dynamic whole. To grasp substance, rational and logical thinking such as definition, judgment, and reasoning is necessary. On the other hand, to grasp Taiji, Dao, etc., which is a dynamic whole or non-substances, "xiang thinking", which is related to perception and rich in poetic association, is essential. History has taught us a lesson, i.e., when we opened the window to logical thought, we closed that of "xiang thinking". We should remember the words of Xu Guangqi, i.e., "To mingle harmoniously and understand thoroughly so as to excel". /// 重新打开被西方中心论长期遮蔽的 "象思维" 是把握中国传统经典本真的 需要。"象思维" 是人类最本原的思维。语言逻辑部经过 "象思维" 孕育而产生。 用概念思维可以透彻解读西方形上学经典，却未必能透彻解读中国诸家经典。中西 两种思维的不同，源于在 "轴心时期" 产生的基本理念的不同。西方形上学理念从 亚里士多德以降均为不同实体，显示为实体性、对象性、现成性。而中国的太极、 道、心性、禅则显示为动态整体的非实体性、非对象性、非现成性。把握实体，需 要用理性的、逻辑的概念思维，如定义、判断、推理等。而把握动态整体或非实体 的太极、道等，则需要用悟性的、诗意联想的 "象思维"。历史的经验教训是:在我 们打开逻辑概念思维这扇窗户时，却错误地关闭了 "象思维" 这扇窗户。我们应记 住徐光启的箴言 "会通以超胜"。. (shrink)

If anthropogenesis was a transition from nature to society and the Neolithic revolution culminated in the breakthrough of human beings into history, then the appearance of cities on our planet, the "urban revolution," marked the rise of civilization, mankind's induction into the spiritual universe. The rise of cities marks the onset of what K. Jaspers called the Axial Period" (eighth-second centuries B.C.). This is the period in which the spiritual preconditions of humanity took shape: the Bible, the (...) Iliad and Odyssey, ancient philosophy and Greek culture, the Upanishads, Zoroastrianism, Taoism, and Confucianism. In world culture the city proved itself as a powerful mediator between the earth and the heavens. (shrink)

To grasp the truth in traditional Chinese classics, we need to uncover the long obscured xiang 象 (image) thinking, which has long been overshadowed by Occidentalism. xiang thinking is the most fundamental thought of human beings. The logic of linguistics all comes from xiang thinking . Through conceptual thinking, people can understand Western classics on metaphysics, yet they may not completely understand the various schools of Chinese classics. The difference between Chinese and Western ways of thinking originated in the difference (...) of the basic views developed in the Axial period . Since Aristotle, Western metaphysical ideas have all been manifested in substantiality, objectivity, and being ready-made, whereas Chinese Taiji, Dao, Xin-xing, and Zen were manifested in the non-substantiality, non-objectivity, and non-ready-made-ness of a dynamic whole. To grasp substance, rational and logical thinking such as definition, judgment, and reasoning is necessary. On the other hand, to grasp Taiji, Dao, etc., which is a dynamic whole or non-substances, xiang thinking , which is related to perception and rich in poetic association, is essential. History has taught us a lesson, i.e., when we opened the window to logical thought, we closed that of xiang thinking . We should remember the words of Xu Guangqi, i.e., To mingle harmoniously and understand thoroughly so as to excel. (shrink)

‘Faith and knowledge’ in Auch eine Geschichte der Philosophie. On the Role of Philosophy in Post-Secular Society This article focuses on three aspects that might clarify the quintessence of Habermas’ position regarding the relation between faith and knowledge in his book, Auch eine Geschichte der Philosophie. First, a concise overview is given of the role of this specific theme in Habermas’ oeuvre as a whole (from his earliest to his later writings), that may help to illuminate why his so-called shift (...) with regard to the relation between faith and knowledge is in need of modification. Subsequently, the question is raised as to the possible role philosophy may still play for Habermas in the contemporary climate of so-called post-secular thought. Finally, some critical remarks are formulated concerning his genealogical reconstruction, in particular his treatment of respectively the axial period, the double face of nominalism and the specific status of a philosophical, conceptual translation of religious contents. (shrink)

If new Platos or Buddhas were to appear today, what would they say about the nature of reality, the human condition and the way to happiness?The period 800-200 b.c.e. the so-called Axial Age was the time when Old World pioneering philosophers and religious teachers laid down the basic ideas by which people have been living ever since. Today those great religious and cultural traditions are coming to an end. We are entering a new Axial Age.Don Cupitt observes (...) that this second Axial Age is one of communication. Everything is accessible to everyone, and everyone can make a contribution. The world is therefore made and remade not by the individual genius, but by a change in the general consensus. Cupitt describes the emergent religion and philosophy of the new Axial Period in clear and accessible language. He predicts that, while it may seem very strange at first, we will learn to love it. (shrink)

Confucianism can be analyzed at three levels of ideas: life as existence (Sein) itself; the Confucian metaphysics about metaphysical beings; and the Confucian doctrines about tangible existences. In the eyes of Confucians, life itself is displayed as the feeling of benevolence in the first place. To reconstruct Confucianism is to return to life and perceive it as a fundamental source. That means to historically return to the original Confucianism during and even before the Axial Period, in essence it (...) is to simultaneously return to our immediate life itself, and then on this basis to reconstruct both Confucian metaphysics and Confucian doctrines about tangible existences. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Sacred Game: The Role of the Sacred in the Genesis of Modern Literary FictionAndrew J. McKennaThe Sacred Game: The Role of the Sacred in the Genesis of Modern Literary Fiction, by Cesareo Bandera; 318 pp. University Park: Pennsylvania State University Press, 1994, $16.50.When we consider the early relations of philosophy and literature, we most often think of Republic X and about degrees of separation between reality and (...) its image. That is a mistake, according to Cesareo Bandera, who shows in his deft reading of Laws that Plato expelled the poets chiefly because of their threat to the difference between sacred and profane: their mournful harmoniae polluted sacred rites. In this Plato is closer to the religious world examined by Durkheim, where the absolute difference between sacred and profane alone guarantees all other differences. Aristotle is shown to be starkly misleading here, since his Poetics discuss tragedy as if it had nothing to do with the ritual practices in which it originates. His vaunted realism can only save poetry—and ontological appearances—by ignoring, by virtually expelling the sacred from its purview.This expulsion of the sacred from the horizon of our rationality is the thematic core of Bandera’s argument about modern literary fiction as it [End Page 189] emerges in the Renaissance. He does not bring the religious back to our attention to enthrall us with it anew, but to explain via formidable literary and historical scholarship how we stand with respect to it, and how we misunderstand our enlightened disrespect for it. Our modern scientific spirit, our really amazing freedom of inquiry, has a different genealogy than we commonly suppose.It is not primarily philosophy which grounds our humanist irreverence, but our Western religious tradition, which Bandera reads, along with René Girard, Roberto Calasso, and Marcel Gauchet, as a uniquely desacralizing agency in culture. His book’s central endeavor is to expand the implications of Girard’s sacrificial theory of social formation across close readings of ancient and Renaissance literature and criticism in order to show the constraints on rationality within a culture where the sacred veiled human violence. According to this view, that veil is rent irreparably with the revelation of the innocent victim as the vantage point from which to interpret the murderous fury of the crowd, however ritualized as awe for the god(s), or as art. A stunning analysis of Virgil (with an assist from Michel Serres’s reading of Lucretius) reveals a writer holding back from his appalled understanding of violent foundations. With the Renaissance, art is cannily deritualized; not pious Aeneas, born of a goddess, but Don Quixote, born in prison, sets the course for modern fiction.Bandera’s astute readings of Renaissance literature and criticism shed decisively new light on the significance of this axial period, poised at the fulcrum of his argument. His vast and probing research reminds us how modern literary fiction nourished its self-consciousness and freedom amidst lavish and vehement debate over mixing the human and divine. Stripped of the taboos limiting classical thought, the sacred’s monopoly on violence had eroded to reveal individual culpability—but also vast, new possibilities for thought and action. A clear ethical impulse accompanies these readings, in which Calderon and Cervantes are shown to deprive us of a sacred alibi for human violence, which is now a matter for me to resolve with my neighbor. Organically cultural imperatives lose ground to a sense of individual responsibility, which Bandera traces back to the historically documented ascendancy of devotio moderna in late medieval Europe.Despite and because of debates over its cultural role, Renaissance literature’s very marginality freed it to explore every dimension of human error. And we learn how those who unwittingly conspire to resacralize it, from Tasso and Shelley through Arnold and Frye, only continue to play the sacred game that caused shudders in Plato and inspires just plain silliness among our own critical anarchs and demystifyers.Bandera’s net is cast wide and deep, including a bracing debate with Milbank and Blumenberg, whose sweep he emulates successfully, and whose powerful analyses he corrects. Witty and adroit scrutiny of our “sacred allergy” extends... (shrink)

Two theme–setting quotations introduce this essay—that of Yeats's falcon, deaf to the falconer's call, adrift in space above the blood–dimmed tide, counterpoised to Pierre Teilhard de Chardin's call to abandon old nationalistic prejudices and build the earth. With primary references to the thought of Teilhard, along with, among others, to Ewert Cousins, Andrew M. Greeley, Karl Jaspers, Marshall McLuhan, Ilya Prigogine, Karl Rahner, Leonard Swidler, David Tracy, and Alfred North Whitehead, I argue that the most crucial intellectual paradigm shift of (...) the twenty–first century will challenge humanity to take the turn from uncritical attachment to rigid absolutism or atomistic fragmentation toward a sense of open–ended, off–centered centeredness and fluid connections—from a static to a dynamic model of reality. Central to my argument is the Teilhardian reinterpretation of the Christian metaphors of creation, fall, incarnation, salvation, and the eschaton in the evolutionary terms of the emergence of cosmic consciousness from the chrysalis of the world of the past—from chaos to order, from biosphere via noosphere to theosphere. Facilitated by the exponential growth of populations, collaborative research, science, technology, and global communication (most dramatically manifested by the Internet), this emergent understanding of what it means to be human can, first, foster the awareness that in humanity evolution has become conscious of itself, and then, gradually, precipitate the formation of “the global village” (the mystical body of Christ), as respectful dialogue replaces diatribe and the dualistic pugilism of Samuel Huntington's “Clash of Civilizations” is gradually transformed into a nonadversarial mentality that values shared humanity and a common purpose. Thus, eons hence, empowered by love–energy, the transmutation of the human into the ultra–human can take the ultimate quantum leap into a yet higher dimension where spirit/energy is no longer in need of flesh/mass, and Earth can be safely left behind. (shrink)

A philosopher‐poet‐theologian ponders the implications of the multimillion‐year biogenetic process that produced Homo sapiensand is beginning to reveal itself ever more clearly as evolution of the mind and consciousness. As meaning trappers and makers, called to actualize the divine image imprinted upon us, we are now facing biological and cultural evolution with deliberate human input as well as the evolution of evolution. As communicating animals that are becoming ever more aware of our adaptive behavior, we have the potential of affecting (...) our own destiny by listening to the spirit within and nurturing the genes and memes that give rise to physical, intellectual, creative, and moral excellence. In the matrix of cyberspace we have the opportunity to heal the two‐culture split, to reinvent ourselves, to incubate/weave the emergent religions of the future, and to create our multiple “Ways” appropriate to the dawning Age of Global Dialogue. (shrink)

This chapter examines the lost legacy of John Stuart-Glennie (1841-1910), a contributor to the founding of sociology and a major theorist, whose work was known in his lifetime but disappeared after his death. Stuart-Glennie was praised by philosopher John Stuart Mill, was a friend of and influence upon playwright George Bernard Shaw, and was an active contributor to the fledgling Sociological Society in London in the first decade of the twentieth century. Stuart-Glennie’s most significant idea in hindsight was his theory (...) of what he termed in 1873, “the moral revolution,” delineating the revolutionary changes across different civilizations in the period 2,500 years ago, roughly centered around 500-600 BCE. This is the era currently known as “the axial age,” after Karl Jaspers coined that term in 1949. Stuart-Glennie’s theory of the moral revolution is framed within a three-stage view of history, the first of which involved an outlook he characterized as “panzooinism,” and sometimes as “naturianism.” This theory of aboriginal and early civilizational outlooks is also notable and worthy of consideration in contemporary context, and as a contribution to “the new animism.” The chapter concludes by considering whether the moral revolution/axial age, whose effects have continued for the past 2500 years, is sustainable in the age of the unsustainable Anthropocene. (shrink)

The Axial Age is an expression invented by Karl Jaspers to refer to a period around the middle of the first millennium, or running from the middle of the first millennium to its end, during which a range of major religions either emerged or were transformed in different places around the world: Confucianism and Taoism in China, Hinduism and Buddhism in India, Zoroastrianism in Persia, Platonism in Greece, and prophetic Judaism in Palestine.1 Platonism, to be sure, is not (...) exactly a religion, and its emphasis on dialogical argument clearly sets it off from the other traditions with which, nevertheless, it bears important affinities. The religions or philosophies of... (shrink)

Purpose. The study is aimed at considering self-reflection through an analysis of the features of internal dialogue in ancient texts in order to identify signs of human’s mythological and philosophical thinking. Theoretical basis of the work is the contemplation of a person’s self-reflection in the context of his internal dialogue, through which his own human existence, his subjective and creative comprehension of the world manifest. New meanings are created and shared with others in this mental space, in particular, in crisis (...) periods of personal and social life. Therefore, the ancient Egyptian vision of man’s nature, consciousnesses and dialogism of the Self is viewed through the prism of modern philosophical concepts and as the basis for the emergence of a philosophical worldview itself. Originality. The analysis from the viewpoint of the philosophical anthropology in the text "The Dispute of a Man with His Ba" showed the opportunity of considering it not only in the context of internal dialogue, but also as a confirmed internal dialogue, which expresses itself in external speech. Comparing the mythical thinking of a man in his cohesiveness with others and the philosophical thinking of a dialogical Self, the authors come to the conclusion that it is necessary to distinguish between internal dialogues with oneself and with the introjects of others, which can be either Double or Interlocutor. It has been revealed that internal dialogues in ancient times played an important role both in structuring social chaos and in overcoming personal crisis states. This is precisely from such self-reflection that philosophy emerges as a certain discourse and a new type of thinking. Conclusions. The analysis of the text "The Dispute of a Man with His Ba" speaks about the emergence of philosophical discourse in the XXII-XXI centuries BC, on the basis of which we can conclude concerning the earlier, in comparison with K. Jaspers’s definition, the transition of mankind from the cognitive revolution to a new phase of the development. (shrink)

English summary: Although the idea of a Euro-Asian Axis Age can be traced back to the pioneer of Iranian studies, Anquetil Duperron, ancient Iran usually plays only a minor role in the 20th century Axis Age theory founded by Karl Jaspers, which revolves around the recording and explanation of rationality. In this investigation of the history of Ancient Iranian rationality, Gotz Konig first points out which theory-immanent moments in Jasper's basic text The Origin and Goal of History (1949) may have (...) favored this omission. Examplary analyses show how minimal changes in the ritual, a change in the configuration of intellectual capacity, or the replacement of a metaphysical concept of order by a legal one open up paths that are oriented towards certain central axial categories. A concluding study of the dialectic of the Axis Age shows how the Achaemenid period (6th-4th century BC) can be regarded in various respects as the true Axis Age of Iran, but ultimately misses and reverses its own rational measures. German description: Obgleich sich der Gedanke einer euro-asiatischen Achsenzeit bis auf den Pionier der Iranistik Anquetil Duperron zuruckfuhren lasst, so spielt der antike Iran in der von Karl Jaspers begrundeten Achsenzeittheorie des 20. Jahrhunderts, die um die Erfassung und Erklarung von 'Rationalitat' kreist, in der Regel nur eine Nebenrolle. Gotz Konig stellt in seinen Untersuchungen zur altiranischen Rationalitatsgeschichte zunachst heraus, welche theorieimmanenten Momente in Jaspers Basistext Vom Ursprung und Ziel der Geschichte (1949) dieses Vergessen begunstigt haben konnen. In Beispielanalysen wird gezeigt, wie durch minimale Veranderungen des Rituals, durch einen Wandel in der Konstellation geistiger Vermogen oder durch die Ersetzung eines metaphysischen durch einen rechtlichen Ordnungsbegriff Wege (im antiken Ost- wie sodann West-Iran) eroffnet werden, die sich auf bestimmte axiale Zentralkategorien hin ausrichten. Eine abschliessende Studie zur Dialektik der Achsenzeit zeigt, wie die Periode der Achameniden (6.-4. Jahrhundert v.Chr.) zwar in verschiedener Hinsicht als die eigentliche Achsenzeit Irans betrachtet werden kann, letztlich aber die eigenen, von ihr aufgestellten rationalen Massstabe verfehlt und verkehrt. (shrink)

Somites are transient structures which represent the most overt segmental feature of the vertebrate embryo. The strict temporal regulation of somitogenesis is of critical developmental importance since many segmental structures adopt a periodicity based on that of the somites. Until recently, the mechanisms underlying the periodicity of somitogenesis were largely unknown. Based on the oscillations of c-hairy1 and lunatic fringe RNA, we now have evidence for an intrinsic segmentation clock in presomitic cells. Translation of this temporal periodicity into a spatial (...) periodicity, through somite formation, requires Notch signaling. While the Hox genes are certainly involved, it remains unknown how the metameric vertebrate axis becomes regionalized along the antero–posterior (AP) dimension into the occipital, cervical, thoracic, lumbar, and sacral domains. We discuss the implications of cell division as a clock mechanism underlying the regionalization of somites and their derivatives along the AP axis. Possible links between the segmentation clock and axial regionalization are also discussed. (shrink)

In the course of their disciplinary consolidation during the 19th and 20th centuries, the social sciences came increasingly to be less historically orientated. Analogously, global history became increasingly a marginal concern for professional historical scholarship. At the present juncture, however, there is a coincidence of a rethinking of the formation of modernity in cultural terms and the need to locate European modernity in a global context. Social theory must be able to provide an account of global historical developments that is (...) less constrained and biased than modernization theory, even in the new garb of globalization studies, but significantly more elaborate in conceptual terms than current contributions to global history. A rethinking of the formation of modernity has already contributed to a greater appreciation of processes of cultural and ideational transformations. It has also suggested new ways of studying institutional change. It must, however, also be able to locate the specific European trajectory in a global context. The core element in such a research programme is the analysis of three major periods of global cultural crystallization, namely the Axial Age, the ecumenical renaissance, and the formation of modernity. The rationale and the contours of this research programme are outlined. (shrink)

Somites are transient structures which represent the most overt segmental feature of the vertebrate embryo. The strict temporal regulation of somitogenesis is of critical developmental importance since many segmental structures adopt a periodicity based on that of the somites. Until recently, the mechanisms underlying the periodicity of somitogenesis were largely unknown. Based on the oscillations of c-hairy1 and lunatic fringe RNA, we now have evidence for an intrinsic segmentation clock in presomitic cells. Translation of this temporal periodicity into a spatial (...) periodicity, through somite formation, requires Notch signaling. While the Hox genes are certainly involved, it remains unknown how the metameric vertebrate axis becomes regionalized along the antero–posterior (AP) dimension into the occipital, cervical, thoracic, lumbar, and sacral domains. We discuss the implications of cell division as a clock mechanism underlying the regionalization of somites and their derivatives along the AP axis. Possible links between the segmentation clock and axial regionalization are also discussed. BioEssays 22:72–83, 2000. ©2000 John Wiley & Sons, Inc. (shrink)

Organismal form arises by the coordinated movement, arrangement, and activity of cells. In metazoans, most morphogenetic programs that establish the recognizable body plan of any given species are initiated during the developmental period, although in many species growth continues throughout life. By comparing the cellular and molecular development of the bilaterians (bilaterally symmetrical animals) to the development of their closest outgroup, the cnidarians, it appears that morphogenesis and the cell fate specification associated with germ layer formation during the process (...) of gastrulation are separately controlled by two distinct downstream pathways (canonical and planar cell polarity) of Wnt signaling. Furthermore, a fundamental change in the early developmental program, the positioning of the site of gastrulation, allowed the spatial separation of gene regulatory networks that facilitated the rapid diversification of bilaterian body plans. (shrink)

In the course of their disciplinary consolidation during the 19th and 20th centuries, the social sciences came increasingly to be less historically orientated. Analogously, global history became increasingly a marginal concern for professional historical scholarship. At the present juncture, however, there is a coincidence of a rethinking of the formation of modernity in cultural terms and the need to locate European modernity in a global context. Social theory must be able to provide an account of global historical developments that is (...) less constrained and biased than modernization theory, even in the new garb of globalization studies, but significantly more elaborate in conceptual terms than current contributions to global history. A rethinking of the formation of modernity has already contributed to a greater appreciation of processes of cultural and ideational transformations. It has also suggested new ways of studying institutional change. It must, however, also be able to locate the specific European trajectory in a global context. The core element in such a research programme is the analysis of three major periods of global cultural crystallization, namely the Axial Age, the ecumenical renaissance, and the formation of modernity. The rationale and the contours of this research programme are outlined. (shrink)

Christopher Dawson identified with sociology, wrote extensively for the original Sociological Review, was a stalwart of the Sociological Society in the interwar years, achieved international recognition as a sociologist, engaged with Karl Mannheim and the Moot, and in the postwar period defended meta-history and the sociologically oriented historical work of people like Marc Bloch. He ultimately became regarded as the greatest Catholic historian of the twentieth century, and became a Harvard Professor and a cult figure for American and European (...) Catholics. This paper describes this remarkable trajectory, his absence from the later self-understanding of British sociology, and his key ideas, including his Bellah-like account of the axial age and his extensive response to Weber’s Protestant Ethic and to the extension of these ideas in Ernst Troetlsch. (shrink)

In a recent publication, Wikramanayake and colleagues have implicated the canonical Wnt/β-catenin signaling pathway as a mediator of axial polarity and germ-layer specification in embryos of the cnidarian Nematostella.1 In this anthozoan, β-catenin is localized in nuclei of blastomeres in one region of the 16- to 32-cell embryo whose descendants subsequently form the entoderm of the embryo. They claim that the pattern of nuclear localization is significant for two reasons: (1) when nuclear localization of β-catenin was inhibited, gastrulation does (...) not occur, and (2) when localization of β-catenin took place in all cells of the pregastrula embryo, the number of entodermal cells increases. Since the Wnt/β-catenin signaling pathway also plays a role in establishing axial polarity and specifying endoderm and mesoderm in a number of bilaterians,2-6 Wikramanayake et al. imply that this developmental mechanism is an evolutionary inheritance from a radially symmetrical ancestor. Some of the gaps in the current evidence, which must be filled to evaluate their interpretation, are discussed. BioEssays 26:474–478, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

Perlecan is a ubiquitous proteoglycan of basement membrane and vascularized tissues but is also present in articular cartilage, meniscus and intervertebral disc, which are devoid of basement membrane and predominantly avascular. It is a prominent pericellular proteoglycan in the transitory matrix of the cartilaginous rudiments that develop into components of diarthrodial joints and the axial skeleton, and it forms intricate perichondrial vessel networks that define the presumptive articulating surfaces of developing joints and line the cartilage canals in cartilaginous rudiments. (...) Such vessels have roles in the nutrition of the expanding cell numbers in the developing joint. Perlecan sequesters a number of growth factors pericellularly (FGFs, PDGF, VEGF and CTGF) and through these promotes cell signalling, cell proliferation and differentiation. Perlecan also interacts with a diverse range of extracellular matrix proteins, stabilising and organising the ECM, and promoting collagen fibrillogenesis. Perlecan is a prominent pericellular component of mesenchymal cells from their earliest developmental stages through to maturation, forming cell–cell and cell–ECM interconnections that are suggestive of a role in mechanosensory processes important to tissue homeostasis. BioEssays 30:457–469, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

Chondrogenesis is a key process in skeletogenesis since endochondral ossification requires the formation of a cartilaginous template. Knowledge of molecular mechanisms regulating chondrogenesis is extremely valuable not only to understand many human disorders but also in regenerative medicine. Embryonic skeletogenesis is an excellent model to study this mechanism. Most cartilages share the cellular basis underlying chondrogenesis but the high heterogeneity in morphologies of the different skeletal elements appears to be generated by differential participation of a variety of chondrogenic signals. Here (...) we overview the regulatory factors responsible for chondrogenesis concluding that early chondrogenic signals for the digit cartilages differ from those implicated in the formation of other axial and appendicular skeletal components. BioEssays 29:725–737, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

The RecA family proteins mediate homologous recombination, a ubiquitous mechanism for repairing DNA double‐strand breaks (DSBs) and stalled replication forks. Members of this family include bacterial RecA, archaeal RadA and Rad51, and eukaryotic Rad51 and Dmc1. These proteins bind to single‐stranded DNA at a DSB site to form a presynaptic nucleoprotein filament, align this presynaptic filament with homologous sequences in another double‐stranded DNA segment, promote DNA strand exchange and then dissociate. It was generally accepted that RecA family proteins function throughout (...) their catalytic cycles as right‐handed helical filaments with six protomers per helical turn. However, we recently reported that archaeal RadA proteins can also form an extended right‐handed filament with three monomers per helical turn and a left‐handed protein filament with four monomers per helical turn. Subsequent structural and functional analyses suggest that RecA family protein filaments, similar to the F1‐ATPase rotary motor, perform ATP‐dependent clockwise axial rotation during their catalytic cycles. This new hypothesis has opened a new avenue for understanding the molecular mechanism of RecA family proteins in homologous recombination. BioEssays 30:48–56, 2008. © 2007 Wiley Periodicals, Inc. (shrink)

Summary The twofold objective of this study is (1) to identify and give a brief review of the historical development of the various designs of early (pre-1850) telescope eyepieces, and (2) to determine by measurements and calculations the axial and lateral chromatic aberrations of a number of extant eyepieces from that period in order to provide basic data on which to judge the relative quality of different eyepiece forms. Eight distinct types of eyepieces containing one to five lens (...) elements are discussed and illustrated. The second objective was addressed by measuring the focal lengths of the individual lens elements and the lens spacings in each eyepiece. The data were processed by a ray-tracing program that yields the chromatic aberration (CA) and focal length of each of the eyepieces. Twenty-one telescopes from that period were studied in this way. Similar calculations were also made using data available in the literature on several additional historic telescopes. The conclusions drawn from the data are: (1) Telescopes with Galilean eyepieces have a smaller CA than those with Keplerian or Huygens eyepieces. (2) The two-lens Keplerian terrestrial eyepieces are demonstrated to have larger axial and lateral CA than any of the other eyepiece types. (3) Calculations from examples of telescopes by Divini and Campani for which data were available indicate that while the axial CAs of the two were the same, Campani's instrument had a much smaller lateral CA. (4) Five element eyepieces were found to be better corrected for CA than the early four-lens systems that replaced them. (5) This study tends to confirm the speculation that the reason makers of early achromatic telescopes overcorrected the objective lenses was to compensate for the CA of the eyepieces. (shrink)

Western philosophy and the tightrope between faith and knowledge In Auch eine Geschichte der Philosophie (2019), Habermas develops a new view of the history of philosophy. Dating philosophy back to the axial age, he presents its history as the result of a collective learning process, spanning a period of three millennia. In this new approach he highlights the crucial importance of faith and religion which resulted in a specific constellation of belief and knowledge that, though unique to the (...) West, has universal import, and led to greater ‘reasonable freedom (Vernüftige Freiheit). In Habermas’ view The West’s Judeo-Christian heritage was not a passing phase in the emergence of modern thought and politics, but contributed its essential core. Though sympathetic to the idea of learning processes spanning many centuries, one may ask whether reasoning and learning processes always tend to lead, as Habermas claims, in the direction of greater freedom instead of its opposite. In this respect Habermas could have learnt more from the sceptical tradition in philosophy and its persistent interest in the various ways in which reasoning processes are non-cognitively embedded in human nature and society and influence the direction these processes take. (shrink)

1. What is Korean Philosophy? 2. What is Philosophy? : Philosophy as Axial Ideas, and Philosophy as Modern ideas 3. What are the distinctions of Korean Philosophy? 1. What is Korean Philosophy? What is Philosophy? It represents human, universal ideas. Does there exist Korean Philosophy that could represent the prevalent and universal ideas among Koreans, within the Korean regions? There are two popular meanings of Philosophy: a narrow meaning and a broad one. Korean Philosophy does not exist as philosophy (...) within the narrow meaning. Philosophy (philosophy = philia+sophia) means “love (philia) of wisdom (sophia)” in the narrow sense that appeared as a demotic term in ancient Greece, and it became a technical term afterward. In the broad sense of philosophy,there are Arabic, Indian, and Chinese Philosophy. They mainly declare their existence through their respective philosophical histories. What is Korean Philosophy? In the narrow definition of ancient Greece, Korean Philosophy first appeared in the Modern Age (1860 A.D.). But In the broad definition of Arabia, India, and China, Korean Philosophy first appeared in “Age of Three Kingdoms of Korea” (37 B.C. ~688 A.D.). Is there a distinct, Korean Philosophy? Korean Philosophy can be defined in two ways: by the philosophy of the Axial Idea and by the philosophy of modern ideas. There are three periods in the history of Korean Philosophy: Korean original, traditional, and modern philosophy. Is there a distinct, Korean Philosophy? The distinctions of the Philosophy native to Korea are based on: 1) contents of “Josunchendook” (Sanhaegyung) 2) terms of “Gojosun,” (Samgukyusa) 3) “Punglu” (Samguksagi) 4) “Chenbugyung” (Handangogi). In these texts are these concepts: 1) the ideas of human respect in “Josunchendook”, 2) the philosophy of the mutual, respectful relations in “Gojosun”, 3) the synthesis ideas from three doctrines - Confucianism, Taoism and Buddhism-in “Pungludo”, and 4) an integration of these three concepts (1 to 3) in“Chenbugyung”; their characteristic is state philosophy, and is seen as modern inter-subjectivity. The distinction of Korean traditional philosophy is one that contains thorough, synthetic ideas (e.g., Wonhyo's idea of one Buddhism that contains all Buddhist sects, Euichon's Chentaejong, Jinul's Jogaejong and so on). These ideas have achieved international renown due to their thoroughness and precision. All types of Korean, traditional philosophy have the trait of thoroughness, whether they stem from primarily Buddhist and Confucian thought. Korean modern philosophy includes the philosophical products (or thoughts) of seven Korean national societies of philosophy. Korean modern philosophy must study modern Korea society. It is changing the Candle spiritual Revolution.This Revolution claims not modern Rights of freedom, equality, and benevolence, but Rights to live all lives altogether. It is happening in the background of two fears: a fear of crazy ox and a fear of distrust society system. The Subject of candle Revolution is mass in the streets, networks, and homes. They have both sunin and democratic citizen minds. While candles fire in the streets, internets, and homes, Candle Revolution is continuing forever in Korean mind. (shrink)

L’article propose une reconstruction systématique de la théorie du sacré de Joas. Après avoir caractérisé le profil disciplinaire de Joas, qui est un spécialiste de la théorie sociale et de la sociologie historique, et présenté sa démarche, qui lie pragmatisme et herméneutique, on montre comment la théorie du sacré de Joas s’enracine dans sa théorie de la genèse des valeurs. Pour Joas, cette genèse se noue dans des expériences de formation de soi et d’auto-transcendance. Ce sont ces expériences, qui peuvent (...) être aussi bien collectives (Durkheim) qu’individuelles (James), que Joas qualifie d’expériences du sacré. Ces expériences sont susceptibles d’une articulation religieuse. La religion est donc un mode possible de l’interprétation du sacré. Mais cette modalité est elle-même susceptible de prendre des formes très diverses, recourant ou non à la catégorie de la transcendance, qui représente la découverte majeure de ce qu’on appelle depuis Karl Jaspers la période axiale – une thématique centrale dans l’œuvre de Joas depuis une quinzaine d’années. C’est sur cette base que Joas développe son histoire de la sacralisation et de la désacralisation, comme alternative au récit wébérien du désenchantement. (shrink)

This study focuses on the experimental and philosophical analysis of the meaning of life in death situation, according to Wittgenstein’s way of life and sayings during the war. The method of extraction and analysis of information is grounded theory. For this purpose, Wittgenstein’s writings such as his letters and memories, and other’s texts about his life and his internal moods were analyzed. After analyzing the collected information and categorizing them in frames of open codes, axial codes, etc. we recognized (...) that Wittgenstein's point of view in death situation was supernatural God-centered. By reading Tolstoy gospel and Dostoyevsky's works, Wittgenstein has reached a kind of religious awakening in that period of his life. But before and after the war period he had a naturalistic point of view toward the meaning of life, in which moral values are in the core. (shrink)

CtBP family proteins predominantly function as transcriptional corepressors. Studies with mutant mouse suggest that the two mouse genes, Ctbp1 and Ctbp2, play unique and redundant gene regulatory roles during development.1 Ctbp1-deficient mice are viable, but are small and die early, while Ctbp2 deficiency leads to embryonic lethality. Ctbp2-null mutation causes defects in axial patterning, heart morphogenesis and neural development. The Ctbp2 mutant phenotype is more severe in the absence of Ctbp1. The studies with Ctbp2 mutant embryos suggest that CtBP (...) can also activate transcription. A plant CtBP homolog, Angustifolia (AN), has recently been identified.2, 3 AN controls polar elongation of leaf cells via the microtubule cytoskeleton. Microarray analysis suggests that AN also functions as a transcriptional repressor. Thus, the CtBP family proteins control cellular processes by serving as transcriptional activators and regulators of the cytoskeleton as well as transcriptional corepressors. BioEssays 25:9–12, 2003. © 2002 Wiley Periodicals, Inc. (shrink)

In the minds of many, Hox gene null mutant phenotypes have confirmed the direct role that these genes play in specifying the pattern of vertebrate embryos. The genes are envisaged as defining discrete spatial domains and, subsequently, conferring specific segmental identities on cells undergoing differentiation along the antero‐posterior axis. However, several aspects of the observed mutant phenotypes are inconsistent with this view. These include: the appearance of other, unexpected transformations along the dorsal axis; the occurrence of mirror‐image duplications; and the (...) development of anomalies outside the established domains of normal Hox gene expression. In this paper, Hox gene disruptions are shown to elicit regeneration‐like responses in tissues confronted with discontinuities in axial identity. The polarities and orientations of transformed segments which emerge as a consequence of this response obey the rules of distal transformation and intercalary regeneration. In addition, the incidence of periodic anomalies suggests that the initial steps of Hox‐mediated patterning occurs in Hensen's node. As gastrulation proceeds, mesoderm cell cycle kinetics impose constraints upon subsequent cellular differentiation. This results in the delayed manifestation of transformations along the antero‐posterior axis. Finally, a paradigm is sketched in which temporal, rather than spatial axial determinants direct differentiation. Specific, testable predictions are made about the role of Hox genes in the establishment of segmental identity. (shrink)

Summary The twofold objective of this study is (1) to identify and give a brief review of the historical development of the various designs of early (pre-1850) telescope eyepieces, and (2) to determine by measurements and calculations the axial and lateral chromatic aberrations of a number of extant eyepieces from that period in order to provide basic data on which to judge the relative quality of different eyepiece forms. Eight distinct types of eyepieces containing one to five lens (...) elements are discussed and illustrated. The second objective was addressed by measuring the focal lengths of the individual lens elements and the lens spacings in each eyepiece. The data were processed by a ray-tracing program that yields the chromatic aberration (CA) and focal length of each of the eyepieces. Twenty-one telescopes from that period were studied in this way. Similar calculations were also made using data available in the literature on several additional historic telescopes. The conclusions drawn from the data are: (1) Telescopes with Galilean eyepieces have a smaller CA than those with Keplerian or Huygens eyepieces. (2) The two-lens Keplerian terrestrial eyepieces are demonstrated to have larger axial and lateral CA than any of the other eyepiece types. (3) Calculations from examples of telescopes by Divini and Campani for which data were available indicate that while the axial CAs of the two were the same, Campani's instrument had a much smaller lateral CA. (4) Five element eyepieces were found to be better corrected for CA than the early four-lens systems that replaced them. (5) This study tends to confirm the speculation that the reason makers of early achromatic telescopes overcorrected the objective lenses was to compensate for the CA of the eyepieces. (shrink)

The RecA family proteins mediate homologous recombination, a ubiquitous mechanism for repairing DNA double‐strand breaks (DSBs) and stalled replication forks. Members of this family include bacterial RecA, archaeal RadA and Rad51, and eukaryotic Rad51 and Dmc1. These proteins bind to single‐stranded DNA at a DSB site to form a presynaptic nucleoprotein filament, align this presynaptic filament with homologous sequences in another double‐stranded DNA segment, promote DNA strand exchange and then dissociate. It was generally accepted that RecA family proteins function throughout (...) their catalytic cycles as right‐handed helical filaments with six protomers per helical turn. However, we recently reported that archaeal RadA proteins can also form an extended right‐handed filament with three monomers per helical turn and a left‐handed protein filament with four monomers per helical turn. Subsequent structural and functional analyses suggest that RecA family protein filaments, similar to the F1‐ATPase rotary motor, perform ATP‐dependent clockwise axial rotation during their catalytic cycles. This new hypothesis has opened a new avenue for understanding the molecular mechanism of RecA family proteins in homologous recombination. BioEssays 30:48–56, 2008. © 2007 Wiley Periodicals, Inc. (shrink)

This article focuses on Karl Jaspers’s notion of the Axial Age, some of its critical appropriation, and how in particular Habermas has returned to this idea, after several critical engagements with Jaspers’s work through his long scholarly productivity. The article, however, centers on Habermas’s selective and critical use of Jaspers’s notion in his own latest and extensive engagement with what he calls “a genealogy of postmetaphysical thinking.” The goal of the article is to identify the ways in which Habermas (...) is refurbishing Jaspers’s generative concept, but at the same time, how his work on postsecular consciousness opens itself to some liabilities by not taking enough distance from the concept. (shrink)

Thus far most of the scholarship on the axial age has followed Karl Jaspers’ denial that nature could be a significant source and continuing influence in the historical development of human consciousness. Yet more than a half century before Jaspers, the originator of the first nuanced theory of what Jaspers termed the axial age, John Stuart-Glennie, mapped out a contrasting philosophy of history that allowed a central role to nature in historical human development. This essay concerns issues related (...) to my book, From the Axial Age to the Moral Revolution, and begins with a discussion of how I came to uncover the forgotten work of John Stuart-Glennie. Although Jaspers and Stuart-Glennie each drew similar conclusions regarding many of the facts of the moral revolution respectively the Axial Age, there are significant differences in their philosophies of history, concerning, for example the problem, whether history can be regarded deterministically or as an open whole, and whether nature can be a source of profound spiritual significance and even transcendence or whether that realm is limited to historical consciousness. I also briefly discuss two other overlooked contributors, namely D. H. Lawrence, who wrote on the phenomena twenty years before Jaspers, and Lewis Mumford, who is one of the first writers to draw from Jaspers' work. I then respond to four diverse scholarly essays on my book, delineating in the process my own philosophy of history as a progress in precision, paradoxically counteracted by a regressive contraction of mind. (shrink)