Search results for 'ELEMENT-BINDING PROTEIN' (try it on Scholar)

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  1. John Bickle (2006). Reducing Mind to Molecular Pathways: Explicating the Reductionism Implicit in Current Cellular and Molecular Neuroscience. [REVIEW] Synthese 151 (3):411-434.score: 180.0
    As opposed to the dismissive attitude toward reductionism that is popular in current philosophy of mind, a “ruthless reductionism” is alive and thriving in “molecular and cellular cognition”—a field of research within cellular and molecular neuroscience, the current mainstream of the discipline. Basic experimental practices and emerging results from this field imply that two common assertions by philosophers and cognitive scientists are false: (1) that we do not know much about how the brain works, and (2) that lower-level neuroscience cannot (...)
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  2. Syed Hasan Arif (2009). A Ca2+‐Binding Protein with Numerous Roles and Uses: Parvalbumin in Molecular Biology and Physiology. Bioessays 31 (4):410-421.score: 140.0
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  3. James B. Hurley (1995). Recoverin, a Calcium-Binding Protein in Photoreceptors. Behavioral and Brain Sciences 18 (3):497-498.score: 112.0
    Recoverin is a Ca2+-binding protein found primarily in vertebrate photoreceptors. The proposed physiological function of recoverin is based on the finding that recoverin inhibits light-stimulated phosphorylation of rhodopsin. Recoverin interacts with rod outer segment membranes in a Ca2+-dependent manner. This interaction requires N-terminal acylation of recoverin. Four types of fatty acids have been detected on the N-terminus of recoverin, but the functional significance of this heterogeneous acylation is not yet clear.
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  4. Ken Aizawa, A Reply to Bechtel and Mundale.score: 88.0
    One theme in recent philosophical attention to neuroscience has been that closer, more serious attention to actual neuroscientific research, and its results, challenges the familiar view that psychological properties are multiply realized by neuroscientific properties. Shagrir, (1998), presents a number of diverse reasons to think that diversity in neuroscientifically identified structures and properties does not inevitably lead to multiple realization. Bechtel and Mundale, (1999), argue that neuroscientific practice extending over a century contradicts the consequences of the hypothesis that psychological functions (...)
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  5. Igor F. Zhimulev, Elena S. Belyaeva, Tatiana Yu Vatolina & Sergey A. Demakov (2012). Banding Patterns in Drosophila Melanogaster Polytene Chromosomes Correlate with DNA‐Binding Protein Occupancy. Bioessays 34 (6):498-508.score: 88.0
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  6. John Dempsher (1982). Basic Function in the Nervous System - a Unified Theory. Acta Biotheoretica 31 (3).score: 87.0
    A new theory for basic function in the nervous system has recently been proposed (Dempsher, J., 1979a, 1979b; 1980, 1981). The major basic themes of the new theory are as follows: (1) There are two fundamental units of structure and function, the fibre or conducting mechanism, and the neurocentre, where nervous system function as we know it takes place. (2) The nerve impulse is regarded as a mathematical event. The mathematics is the result of a prescribed fusion of energy and (...)
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  7. Edward Chu & Carmen J. Allegra (1996). The Role of Thymidylate Synthase as an RNA Binding Protein. Bioessays 18 (3):191-198.score: 84.0
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  8. Michael J. B. Krieger (2005). To B or Not to B: A Pheromone‐Binding Protein Regulates Colony Social Organization in Fire Ants. Bioessays 27 (1):91-99.score: 84.0
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  9. Katia Ancelin, Christine Brun & Eric Gilson (1998). Role of the Telomeric DNA‐Binding Protein TRF2 in the Stability of Human Chromosome Ends. Bioessays 20 (11):879-883.score: 84.0
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  10. Evelync Friederich, Eric Pringault, Monique Arpin & Daniel Louvard (1990). From the Structure to the Function of Villin, an Actin‐Binding Protein of the Brush Border. Bioessays 12 (9):403-408.score: 84.0
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  11. John W. Chase (1984). The Role of E. Coli Single‐Stranded DNA Binding Protein in DNA Metabolism. Bioessays 1 (5):218-222.score: 84.0
  12. Julie Deschênes‐Furry, Nora Perrone‐Bizzozero & Bernard J. Jasmin (2006). The RNA‐Binding Protein HuD: A Regulator of Neuronal Differentiation, Maintenance and Plasticity. Bioessays 28 (8):822-833.score: 84.0
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  13. Kimitoshi Kohno, Hiroto Izumi, Takeshi Uchiumi, Megumi Ashizuka & Michihiko Kuwano (2003). The Pleiotropic Functions of the Y‐Box‐Binding Protein, YB‐1. Bioessays 25 (7):691-698.score: 84.0
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  14. M. J. Krleger (2004). To H or Not to B: A Pheromone—Binding Protein Re-at Os Colony Social Organization I Nf Ire a Nts. Bioessays 27:9.score: 84.0
     
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  15. Maureen McLeod (1989). Regulation of Meiosis: From DNA Binding Protein to Protein Kinase. Bioessays 11 (1):9-14.score: 84.0
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  16. Melissa Little, Greg Holmes & Patrick Walsh (1999). WT1: What has the Last Decade Told Us? Bioessays 21 (3):191-202.score: 80.0
    When positionally cloned in late 1989, it was anticipated that mutations within the Wilms' tumour suppressor gene (WT1) would prove responsible for this common solid kidney cancer of childhood. Characterisation of the WT1 expression pattern and of the structure of the encoded protein isoforms and their mode of action has now spanned almost a decade. WT1 proteins act as nucleic acid-binding zinc finger-containing transcription factors involved in both transactivation and repression. These activities are facilitated and constrained by interactions with (...)
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  17. Stuart K. Archer, Charles Claudianos & Hugh D. Campbell (2005). Evolution of the Gelsolin Family of Actin-Binding Proteins as Novel Transcriptional Coactivators. Bioessays 27 (4):388-396.score: 77.3
    The gelsolin gene family encodes a number of higher eukaryotic actin-binding proteins that are thought to function in the cytoplasm by severing, capping, nucleating or bundling actin filaments. Recent evidence, however, suggests that several members of the gelsolin family may have adopted unexpected nuclear functions including a role in regulating transcription. In particular, flightless I, supervillin and gelsolin itself have roles as coactivators for nuclear receptors, despite the fact that their divergence appears to predate the evolutionary appearance of nuclear receptors. (...)
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  18. Ronald E. Hileman, Jonathan R. Fromm, John M. Weiler & Robert J. Linhardt (1998). Glycosaminoglycan‐Protein Interactions: Definition of Consensus Sites in Glycosaminoglycan Binding Proteins. Bioessays 20 (2):156-167.score: 76.0
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  19. Susan P. C. Cole & Roger G. Deeley (1998). Multidrug Resistance Mediated by the ATP‐Binding Cassette Transporter Protein MRP. Bioessays 20 (11):931-940.score: 72.0
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  20. Susan Jaken & Peter J. Parker (2000). Protein Kinase C Binding Partners. Bioessays 22 (3):245-254.score: 72.0
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  21. Martino Mona (2008). Binding Consent or Element of Presumed Consent? Conceptualization and Legal Relevance of Advance Health Care Directives in the Context of Multicultural Bioethics. Ethik in der Medizin 20 (3):248-257.score: 72.0
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  22. Spiros A. Vlahopoulos, Stella Logotheti, Dimitris Mikas, Athina Giarika, Vassilis Gorgoulis & Vassilis Zoumpourlis (2008). The Role of ATF‐2 in Oncogenesis. Bioessays 30 (4):314-327.score: 60.0
    Activating Transcription Factor-2 is a sequence-specific DNA-binding protein that belongs to the bZIP family of proteins and plays diverse roles in the mammalian cells. In response to stress stimuli, it activates a variety of gene targets including cyclin A, cyclin D and c-jun, which are involved in oncogenesis in various tissue types. ATF-2 expression has been correlated with maintenance of a cancer cell phenotype. However, other studies demonstrate an antiproliferative or apoptotic role for ATF-2. In this review, we summarize (...)
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  23. Alexander Dibrov, Yvonne Myal & Etienne Leygue (2009). Computational Modelling of Protein Interactions: Energy Minimization for the Refinement and Scoring of Association Decoys. Acta Biotheoretica 57 (4).score: 42.0
    The prediction of proteinprotein interactions based on independently obtained structural information for each interacting partner remains an important challenge in computational chemistry. Procedures where hypothetical interaction models (or decoys) are generated, then ranked using a biochemically relevant scoring function have been garnering interest as an avenue for addressing such challenges. The program PatchDock has been shown to produce reasonable decoys for modeling the association between pig alpha-amylase and the VH-domains of camelide antibody raised against it. We designed a (...)
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  24. Michael Doyle, Lukas Badertscher, Lukasz Jaskiewicz, Stephan Güttinger, Sabine Jurado, Tabea Hugenschmidt, Ulrike Kutay & Witold Filipowicz, The Double-Stranded RNA Binding Domain of Human Dicer Functions as a Nuclear Localization Signal.score: 42.0
    Dicer is a key player in microRNA (miRNA) and RNA interference (RNAi) pathways, processing miRNA precursors and doublestranded RNA into ~21-nt-long products ultimately triggering sequence-dependent gene silencing. Although processing of substrates in vertebrate cells occurs in the cytoplasm, there is growing evidence suggesting Dicer is also present and functional in the nucleus. To address this possibility, we searched for a nuclear localization signal (NLS) in human Dicer and identified its C-terminal double-stranded RNA binding domain (dsRBD) as harboring NLS activity. We (...)
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  25. Pierre Pica (1995). Condition C and Epistemic Contexts : A Case Study of Epithets and Anti-Logophoricity Pronouns in French. In Young-Sun Kim, Byung-Choon Lee, Kyoung-Jae Lee, Kyun-Kwon Yang & Jong-Kuri Yoon (eds.), A Festchrift for Dong-Whee Yang. Hankuk Publishing.score: 36.0
    Epithets and pronominals 'en' and 'y' in French have a variety of Binding properties that are unexpected on conventional approach to Binding Theory. We argue that the linguistic variety observed cross-linguistically (and perhaps, more surprinsingly, within a single language) - derives from the morphological properties of the anaphoric element - which we claim lack number features. Epithets and pronominal like 'en' and 'y' are predicates modifying null but semantically active nouns, and must theefore refer to the Speaker. These properties, we (...)
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  26. Paul A. Wade (2001). Methyl CpG‐Binding Proteins and Transcriptional Repression. Bioessays 23 (12):1131-1137.score: 34.0
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  27. Alan M. Jones & Paruchuri V. Prasad (1992). Auxin-Binding Proteins and Their Possible Roles in Auxin-Mediated Plant Cell Growth. Bioessays 14 (1):43-48.score: 34.0
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  28. Richard D. Cummings & David F. Smith (1992). The Selectin Family of Carbohydrate-Binding Proteins: Structure and Importance of Carbohydrate Ligands for Cell Adhesion. Bioessays 14 (12):849-856.score: 34.0
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  29. Gall David (2012). Control of Neuronal Excitability by Calcium Binding Proteins : A New Mathematical Model for Striatal Fast-Spiking Interneurons. Frontiers in Human Neuroscience 6.score: 34.0
  30. David Hughes & Peter Fantes (1987). Genetics of Calcium‐Binding Proteins in Yeasts. Bioessays 6 (5):229-231.score: 34.0
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  31. Jing‐Jer Lin (1993). What the Papers Say: Telomeric DNA Binding Proteins. Bioessays 15 (8):555-557.score: 34.0
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  32. Raymond J. Owens & Michael J. Crumpton (1984). A New Class of Membrane‐Associated Calcium‐Binding Proteins. Bioessays 1 (2):61-63.score: 34.0
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  33. John Sommerville (1992). What the Papers Say: RNA‐Binding Proteins: Masking Proteins Revealed. Bioessays 14 (5):337-339.score: 34.0
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  34. Joanna Bandorowicz‐Pikula, Rene Buchet & Slawomir Pikula (2001). Annexins as Nucleotide‐Binding Proteins: Facts and Speculations. Bioessays 23 (2):170-178.score: 34.0
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  35. Xose R. Bustelo, Vincent Sauzeau & Inmaculada M. Berenjeno (2007). GTP‐Binding Proteins of the Rho/Rac Family: Regulation, Effectors and Functions in Vivo. Bioessays 29 (4):356-370.score: 34.0
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  36. Mitsunori Fukuda & Katsuhiko Mikoshiba (1997). The Function of Inositol High Polyphosphate Binding Proteins. Bioessays 19 (7):593-603.score: 34.0
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  37. Mitsuhiko Ikura, Masanori Osawa & James B. Ames (2002). The Role of Calcium-Binding Proteins in the Control of Transcription: Structure to Function. Bioessays 24 (7):625-636.score: 34.0
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  38. Michael Joulie, Benoit Miotto & Pierre‐Antoine Defossez (2010). Mammalian Methyl‐Binding Proteins: What Might They Do? Bioessays 32 (12):1025-1032.score: 34.0
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  39. David Landsman & Michael Bustin (1993). A Signature for the HMG‐1 Box DNA‐Binding Proteins. Bioessays 15 (8):539-546.score: 34.0
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  40. Arthur M. Mercurio & Leslie M. Shaw (1991). Laminin Binding Proteins. Bioessays 13 (9):469-473.score: 34.0
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  41. Krzysztof Palczewski, Arthur S. Polans, Wolfgang Baehr & James B. Ames (2000). Ca2+‐Binding Proteins in the Retina: Structure, Function, and the Etiology of Human Visual Diseases. Bioessays 22 (4):337-350.score: 34.0
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  42. Alan P. Wolffe (1994). Structural and Functional Properties of the Evolutionarily Ancient Y‐Box Family of Nucleic Acid Binding Proteins. Bioessays 16 (4):245-251.score: 34.0
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  43. Rosanna K. Olsen, Sandra N. Moses, Lily Riggs & Jennifer D. Ryan (2012). The Hippocampus Supports Multiple Cognitive Processes Through Relational Binding and Comparison. Frontiers in Human Neuroscience 6.score: 30.0
    It has been well established that the hippocampus plays a pivotal role in explicit long-term recognition memory. However, findings from amnesia, lesion and recording studies with non-human animals, eye-movement recording studies, and functional neuroimaging have recently converged upon a similar message: the functional reach of the hippocampus extends far beyond explicit recognition memory. Damage to the hippocampus affects performance on a number of cognitive tasks including recognition memory after short and long delays and visual discrimination. Additionally, with the advent of (...)
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  44. Sarah Gerlo, Julian R. E. Davis, Dixie L. Mager & Ron Kooijman (2006). Prolactin in Man: A Tale of Two Promoters. Bioessays 28 (10):1051-1055.score: 30.0
    The pituitary hormone prolactin (PRL) is best known for its role in the regulation of lactation. Recent evidence furthermore indicates PRL is required for normal reproduction in rodents. Here, we report on the insertion of two transposon-like DNA sequences in the human prolactin gene, which together function as an alternative promoter directing extrapituitary PRL expression. Indeed, the transposable elements contain transcription factor binding sites that have been shown to mediate PRL transcription in human uterine decidualised endometrial cells and lymphocytes. We (...)
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  45. Thomas Ferenci (1989). Selectivity in Solute Transport: Binding Sites and Channel Structure in Maltoporin and Other Bacterial Sugar Transport Proteins. Bioessays 10 (1):1-7.score: 30.0
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  46. Haluk Ögmen Michael H. Herzog, Thomas U. Otto (2012). The Fate of Visible Features of Invisible Elements. Frontiers in Psychology 3.score: 30.0
    To investigate the integration of features, we have developed a paradigm in which an element is rendered invisible by visual masking. Still, the features of the element are visible at other elements (sequential metacontrast). In this sense, we can “transport” features non-retinotopically across space and time. The features of the invisible element integrate with features of other elements if and only if the elements belong to the same spatio-temporal group. In this case, features unconsciously integrate. The mechanisms of this kind (...)
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  47. Roberto Perez‐Torrado, Daisuke Yamada & Pierre‐Antoine Defossez (2006). Born to Bind: The BTB ProteinProtein Interaction Domain. Bioessays 28 (12):1194-1202.score: 30.0
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  48. Ajda Taler‐Verčič & Eva Žerovnik (2010). Binding of Amyloid Peptides to Domain‐Swapped Dimers of Other Amyloid‐Forming Proteins May Prevent Their Neurotoxicity. Bioessays 32 (12):1020-1024.score: 30.0
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  49. P. A. Wade (2001). Methyl CpG-Binding Transcriptional Proteins and Repression. Bioessays 23 (12):1131-1137.score: 30.0
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  50. Rafik I. Beekun & Jamal A. Badawi (2005). Balancing Ethical Responsibility Among Multiple Organizational Stakeholders: The Islamic Perspective. [REVIEW] Journal of Business Ethics 60 (2):131 - 145.score: 28.0
    In spite of a renewed interest in the relationship between spirituality and managerial thinking, the literature covering the link between Islam and management has been sparse – especially in the area of ethics. One potential reason may be the cultural diversity of nearly 1.3 billion Muslims globally. Yet, one common element binding Muslim individuals and countries is normative Islam. Using all four sources of this religion’s teachings, we outline the parameters of an Islamic model of normative business ethics. We explain (...)
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