What sets someone on a life trajectory? This question is at the heart of studies of 21st-century neurosciences that build on scientific models developed over the last 150 years that attempt to link psychopathology risk and human development. Historically, this research has documented persistent effects of singular, negative life experiences on people’s subsequent development. More recently, studies have documented neuromolecular effects of early life adversity on life trajectories, resulting in models that frame lives as disproportionately affected by early negative experiences. (...) This view is dominant, despite little evidence of the stability of the presumably early-developed molecular traits and their potential effects on phenotypes. We argue that in the context of gaps in knowledge and the need for scientists to reason across molecular and phenotypic scales, as well as time spans that can extend beyond an individual’s life, specific interpretative frameworks shape the ways in which individual scientific findings are assessed. In the process, scientific reasoning oscillates between understandings of cellular homeostasis and organisms’ homeorhesis, or life trajectory. Biologist and historian François Jacob described this framework as the “attitude” that researchers bring to bear on their “objects” of study. Through an analysis of, first, historical and contemporary scientific literature and then ethnographic research with neuroscientists, we consider how early life trauma came to be associated with specific psychological and neurobiological effects grounded in understandings of life trajectories. We conclude with a consideration of the conceptual, ontological, and ethical implications of interpreting life trajectories as the result of the persistence of long-embodied biological traits, persistent life environments, or both. (shrink)

ArgumentIn this article, we trace shifting narratives of trauma within psychiatric, neuroscience, and environmental epigenetics research. We argue that two contemporary narratives of trauma – each of which concerns questions of time and psychopathology, of the past invading the present – had to be stabilized in order for environmental epigenetics models of suicide risk to be posited. Through an examination of these narratives, we consider how early trauma came to be understood as playing an etiologically significant role in the development (...) of suicide risk. Suicide, in these models, has come to be seen as a behavior that has no significant precipitating event, but rather an exceptional precipitating neurochemical state, whose origins are identified in experiences of early traumatic events. We suggest that this is a part of a broader move within contemporary neurosciences and biopsychiatry to seelife as post: seeing life as specific form of post-traumatic subjectivity. (shrink)

Abstract The aim of this article is to make use of recent research on `political eros ' in order to clarify the connection that Plato establishes between eros and tyranny in Republic IX, specifically by elucidating the intertextuality between Plato's work and the various historical accounts of Alcibiades. An examination of the lexicon used in these accounts will allow us to resolve certain interpretive difficulties that, to my knowledge, no other commentator has elucidated: why does Socrates blame eros for the (...) decline from democracy into tyranny? What does he mean by ` eros ' here, and what link existed between eros and tyranny in the minds of his contemporaries? And finally, who are the mysterious `tyrant-makers' ( turannopoioí , 572e5-6) who, according to Socrates, introduce a destructive eros in the soul of the future tyrant? After a careful examination of the passage from book IX on the genesis of the tyrannical man (focused on the last stage of the metamorphosis, which is concerned with éros túrannos , 572d-573b), I will offer answers to these questions by turning to the writings of Thucydides, Aristophanes and Plutarch while examining the portrait of Alcibiades that Plato paints in the Alcibiades I and Symposium. (shrink)

Ce texte cherche à montrer que plusieurs allusions textuelles indiquent l'existence d'un lien significatif entre le Choeur de Dionysos et le νυκτερινὸς σύλλογος dans les Lois de Platon. Cette hypothèse inédite se trouve confirmée par un examen attentif des diverses correspondances entre les deux instances, examen qui permet en outre de préciser la nature de leur lien. Il semble d'abord que le Choeur de Dionysos ait pour rôle d'apporter un complément pédagogique de "musique appliquée" à l'élite politique et scientifique de (...) la cité. Plus important encore, le Choeur Dionysien paraît être l'organe idéologique privilégié par lequel les gouvernants du Collège de veille peuvent donner une forme persuasive à leur science et exercer une influence civique puissante sur l'ensemble de la population. (shrink)

Ce texte cherche à montrer que plusieurs allusions textuelles indiquent l'existence d'un lien significatif entre le Choeur de Dionysos et le νυκτ∊ρινος συλλογος dans les _Lois_ de Platon. Cette hypothèse inédite se trouve confirmée par un examen attentif des diverses correspondances entre les deux instances, examen qui permet en outre de préciser la nature de leur lien. Il semble d'abord que le Choeur de Dionysos ait pour rôle d'apporter un complément pédagogique de «musique appliquée» à l'élite politique et scientifique de (...) la cité. Plus important encore, le Choeur Dionysien paraît être l'organe idéologique privilégié par lequel les gouvernants du Collège de veille peuvent donner une forme persuasive à leur science et exercer une influence civique puissante sur l'ensemble de la population. (shrink)

En 1981-82 Foucault a consacré son enseignement au Collège de France à la question du souci de soi antique. À ce cours, publié en 2001, il a donné le titre énigmatique d’«Herméneutique du sujet». Ma communication vise à élucider le sens de ce titre en montrant comment les travaux généalogiques entrepris par Foucault au cours des dernières années de sa vie visaient à combattre un mode de rapport à soi dominé par l’interprétation. Mon but consiste donc à montrer que si (...) le dernier Foucault s’est concentré sur le souci de soi antique, c’était en vue d’opposer une résistance à la tendance contemporaine à l’herméneutique de soi. (shrink)

Helfer opens his book with a series of vigorous reflections that have the virtue of challenging some of the reader’s deeply seated beliefs concerning political emotions. While we moderns see political ambition mostly as a threat to the public good that needs to be checked, ancients, the author suggests, considered that passion in a positive light. Indeed, they regarded political ambition as the manifestation of a powerful desire to achieve noble deeds in the civic sphere, an aspiration they saw as (...) a central feature of human nature. That Alcibiades presents us with the most spectacular example of a man animated by such a passion is uncontentious, no matter how controversial this historical person was. By studying... (shrink)

While specialists of the Platonic corpus often evoke the most remarkable passages of the Statesman or use it to trace the evolution of Plato’s political thought, few invite us to appreciate this difficult text itself. We can, therefore, only revel in the almost missionary zeal with which Dimitri El Murr champions this neglected dialogue in his Savoir et gouverner.The best way to appreciate the Statesman is to recognize its distinct contribution; and what sets this dialogue apart, according to El Murr, (...) is the attention paid to the idea of politics as a form of knowledge possessed by the ruler. This intense focus on the issue of politics as a science—found neither in the Republic nor Laws—is unique to the Statesman.. (shrink)

Michèle Le Doeuff coined the term “déshérence” to describe a phenomenon affecting the relation of women to knowledge. Déshérence reflects the antithetical connection between women and value: if something is socially devalued, women may claim it; if something women already possess reveals itself as valuable, then they have to relinquish it. My article shows how Plato’s Statesman offers a perfect example of déshérence in its two complementary forms. But the article’s primary objective is to shed light on the connection between (...) Plato’s Republic and his Statesman. Indeed, the presence of déshérence becomes clear when considering a perplexing question about the Statesman: What happened to the philosopher queens in this dialogue? If advocating for them was once seen as worth risking a formidable wave of mockery and attacks in the Republic, why are the philosopher queens nowhere to be seen in Plato’s following dialogues? This question leads to a reconsideration of the role of the guardians in the Republic and to a recognition of their presence in the Statesman. As it turns out, those we call “philosopher queens” are still instrumental to what Plato sees as an excellent polis. The reason why we do not see them is that they are not where we expect them to be. (shrink)