7 found
Sort by:
  1. Alexander Powell (2011). Book Review Essay of J. Shapiro, Evolution: A View From the 21st Century. [REVIEW] Genomics, Society and Policy 7:35-43.
  2. Alexander Powell (2009). Molecules, Cells and Minds: Aspects of Bioscientific Explanation. Dissertation, University of Exeter
    In this thesis I examine a number of topics that bear on explanation and understanding in molecular and cell biology, in order to shed new light on explanatory practice in those areas and to find novel angles from which to approach relevant philosophical debates. The topics I look at include mechanism, emergence, cellular complexity, and the informational role of the genome. I develop a perspective that stresses the intimacy of the relations between ontology and epistemology. Whether a phenomenon looks mechanistic, (...)
    Translate to English
    | Direct download  
     
    My bibliography  
     
    Export citation  
  3. Alexander Powell & John Dupré (2009). From Molecules to Systems: The Importance of Looking Both Ways. Studies in History and Philosophy of Biological and Biomedical Sciences 40 (1):54-64.
    Although molecular biology has meant different things at different times, the term is often associated with a tendency to view cellular causation as conforming to simple linear schemas in which macro-scale effects are specified by micro-scale structures. The early achievements of molecular biologists were important for the formation of such an outlook, one to which the discovery of recombinant DNA techniques, and a number of other findings, gave new life even after the complexity of genotype–phenotype
    relations had become apparent. Against this (...)
    Direct download (3 more)  
     
    My bibliography  
     
    Export citation  
  4. Maureen A. O'Malley, Alexander Powell, Jonathan F. Davies & Jane Calvert (2008). Knowledge‐Making Distinctions in Synthetic Biology. Bioessays 30 (1):57-65.
  5. Maureen O'Malley, Alexander Powell, Jonathan Davies & Jane Calvert (2008). Knowledge-Making Distinctions in Synthetic Biology. BioEssays 30 (1):57-65.
    Synthetic biology is an increasingly high-profile area of research that can be understood as encompassing three broad approaches towards the synthesis of living systems: DNA-based device construction, genome-driven cell engineering and protocell creation. Each approach is characterized by different aims, methods and constructs, in addition to a range of positions on intellectual property and regulatory regimes. We identify subtle but important differences between the schools in relation to their treatments of genetic determinism, cellular context and complexity. These distinctions tie into (...)
    Translate to English
    |
     
    My bibliography  
     
    Export citation  
  6. Alexander Powell, Maureen A. O'Malley, Staffan Mueller-Wille, Jane Calvert & John Dupré (2007). Disciplinary Baptisms: A Comparison of the Naming Stories of Genetics, Molecular Biology, Genomics and Systems Biology. History and Philosophy of the Life Sciences 29 (1):5-32.
    Understanding how scientific activities use naming stories to achieve disciplinary status is important not only for insight into the past, but for evaluating current claims that new disciplines are emerging. In order to gain a historical understanding of how new disciplines develop in relation to these baptismal narratives, we compare two recently formed disciplines, systems biology and genomics, with two earlier related life sciences, genetics and molecular biology. These four disciplines span the twentieth century, a period in which the processes (...)
    Direct download (2 more)  
     
    My bibliography  
     
    Export citation  
  7. Alexander Powell, Maureen A. O. Malley, Staffan Muller-Wille, Jane Calvert & John Dupré (2007). Disciplinary Baptisms: A Comparison of the Naming Stories of Genetics, Molecular Biology, Genomics, and Systems Biology. History and Philosophy of the Life Sciences 29 (1):5.
    Direct download  
     
    My bibliography  
     
    Export citation